Literature DB >> 9402703

Are bacterial exotoxins cytokine network regulators?

B Henderson1, M Wilson, B Wren.   

Abstract

Bacterial exotoxins are generally thought to act by damaging cells or altering cell metabolism. However, recent work has established that many exotoxins modulate eukaryotic cell cytokine synthesis. Cytokine induction may play a significant role in exotoxin action, and therapeutic targeting of cytokines could be beneficial in infectious diseases involving bacterial exotoxins.

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Year:  1997        PMID： 9402703     DOI： 10.1016/S0966-842X(97)01125-6

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  7 in total

Review 1.  Bacterial perturbation of cytokine networks.

Authors:  M Wilson; R Seymour; B Henderson
Journal:  Infect Immun       Date:  1998-06       Impact factor: 3.441

2.  The cytotoxic enterotoxin of Aeromonas hydrophila induces proinflammatory cytokine production and activates arachidonic acid metabolism in macrophages.

Authors:  A K Chopra; X Xu; D Ribardo; M Gonzalez; K Kuhl; J W Peterson; C W Houston
Journal:  Infect Immun       Date:  2000-05       Impact factor: 3.441

3.  The streptococcal exotoxin streptolysin O activates mast cells to produce tumor necrosis factor alpha by p38 mitogen-activated protein kinase- and protein kinase C-dependent pathways.

Authors:  Michael Stassen; Christian Müller; Christoph Richter; Christine Neudörfl; Lothar Hültner; Sucharit Bhakdi; Iwan Walev; Edgar Schmitt
Journal:  Infect Immun       Date:  2003-11       Impact factor: 3.441

4.  Cytotoxic necrotizing factor 1 enhances reactive oxygen species-dependent transcription and secretion of proinflammatory cytokines in human uroepithelial cells.

Authors:  Loredana Falzano; Maria Giovanna Quaranta; Sara Travaglione; Perla Filippini; Alessia Fabbri; Marina Viora; Gianfranco Donelli; Carla Fiorentini
Journal:  Infect Immun       Date:  2003-07       Impact factor: 3.441

5.  Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner.

Authors:  Jessica Chu; L Michael Thomas; Simon C Watkins; Luigi Franchi; Gabriel Núñez; Russell D Salter
Journal:  J Leukoc Biol       Date:  2009-08-12       Impact factor: 4.962

6.  Immunoglobulin A1 protease, an exoenzyme of pathogenic Neisseriae, is a potent inducer of proinflammatory cytokines.

Authors:  D R Lorenzen; F Düx; U Wölk; A Tsirpouchtsidis; G Haas; T F Meyer
Journal:  J Exp Med       Date:  1999-10-18       Impact factor: 14.307

Review 7.  Molecular Mechanisms of Mast Cell Activation by Cholesterol-Dependent Cytolysins.

Authors:  Lubica Draberova; Magda Tumova; Petr Draber
Journal:  Front Immunol       Date:  2021-06-23       Impact factor: 7.561
  7 in total

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