| Literature DB >> 9402700 |
Abstract
Rolling circle DNA replication is inherently continuous and unregulated. This 'go-for-broke' strategy works well for lytic phages but is suicidal for plasmids that must coexist with their host. Plasmids have consequently evolved elaborate copy number control systems that operate at the transcriptional, translational and post-translational levels.Mesh:
Substances:
Year: 1997 PMID: 9402700 DOI: 10.1016/S0966-842X(97)01143-8
Source DB: PubMed Journal: Trends Microbiol ISSN: 0966-842X Impact factor: 17.079