Literature DB >> 9400493

Enhanced expression of the mesenchymal marker, vimentin, in hyperplastic versus normal human prostatic epithelium.

C H Fraga1, L D True, D Kirk.   

Abstract

A total of 20 benign prostatic hyperplasia (BPH) tissue samples from 13 patients were evaluated for the coexpression of cytokeratins and vimentin intermediate filaments in the glandular epithelium. Vimentin expression was significantly increased (p < 0.001) in BPH epithelium compared to adjacent "normal" epithelium. The data imply that epithelial/mesenchymal (E/M) transformations may play a role in the pathogenesis of BPH.

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Year:  1998        PMID： 9400493     DOI： 10.1016/s0022-5347(01)64080-1

Source DB:  PubMed          Journal:  J Urol        ISSN： 0022-5347            Impact factor:   7.450


  9 in total

1.  Modulation of the malignant phenotype of human prostate cancer cells by N-(4-hydroxyphenyl)retinamide (4-HPR).

Authors:  M M Webber; D Bello-DeOcampo; S Quader; N D Deocampo; W S Metcalfe; R M Sharp
Journal:  Clin Exp Metastasis       Date:  1999-05       Impact factor: 5.150

Review 2.  The Role of Heat Shock Protein 70 Subfamily in the Hyperplastic Prostate: From Molecular Mechanisms to Therapeutic Opportunities.

Authors:  Xun Fu; Huan Liu; Jiang Liu; Michael E DiSanto; Xinhua Zhang
Journal:  Cells       Date:  2022-06-28       Impact factor: 7.666

3.  Stromal growth and epithelial cell proliferation in ventral prostates of liver X receptor knockout mice.

Authors:  Hyun-Jin Kim; Leif C Andersson; Didier Bouton; Margaret Warner; Jan-Ake Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  2009-01-02       Impact factor: 11.205

4.  Differential protein mapping of ovarian serous adenocarcinomas: identification of potential markers for distinct tumor stage.

Authors:  Yanfei Wang; Rong Wu; Kathleen R Cho; Dafydd G Thomas; Gabrielle Gossner; J Rebecca Liu; Thomas J Giordano; Kerby A Shedden; David E Misek; David M Lubman
Journal:  J Proteome Res       Date:  2009-03       Impact factor: 4.466

5.  Validating antimetastatic effects of natural products in an engineered microfluidic platform mimicking tumor microenvironment.

Authors:  Yiming Niu; Jing Bai; Roger D Kamm; Yitao Wang; Chunming Wang
Journal:  Mol Pharm       Date:  2014-02-24       Impact factor: 4.939

6.  A role for epithelial-mesenchymal transition in the etiology of benign prostatic hyperplasia.

Authors:  Paloma Alonso-Magdalena; Clemens Brössner; Angelika Reiner; Guojun Cheng; Nobuhiro Sugiyama; Margaret Warner; Jan-Ake Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-05       Impact factor: 11.205

7.  Prostate epithelial cell lines form spheroids with evidence of glandular differentiation in three-dimensional Matrigel cultures.

Authors:  S H Lang; R M Sharrard; M Stark; J M Villette; N J Maitland
Journal:  Br J Cancer       Date:  2001-08-17       Impact factor: 7.640

8.  Morphological and immunohistochemical identification of epithelial-to-mesenchymal transition in clinical prostate cancer.

Authors:  Kimberley Kolijn; Esther I Verhoef; Geert J L H van Leenders
Journal:  Oncotarget       Date:  2015-09-15

9.  Transcriptome profiles of carcinoma-in-situ and invasive non-small cell lung cancer as revealed by SAGE.

Authors:  Kim M Lonergan; Raj Chari; Bradley P Coe; Ian M Wilson; Ming-Sound Tsao; Raymond T Ng; Calum Macaulay; Stephen Lam; Wan L Lam
Journal:  PLoS One       Date:  2010-02-11       Impact factor: 3.240
  9 in total

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