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Literature DB >> 9399857

Database of mutations within the adenovirus 5 E1A oncogene.

Abstract

The Ad5 E1A database is a listing of mutations affecting the early region 1A (E1A) proteins of human adenovirus type 5. The database contains the name of the mutation, the nucleic acid sequence changes, the resulting alterations in amino acid sequence and reference. Additional notes and references are provided on the effect of each mutation on E1A function. The database is contained within the Adenovirus 5 E1A page on the World Wide Web at: http://www.geocities.com/CapeCanaveral/Hangar /2541/

Entities: Species

Mesh：

Substances：
Adenovirus E1A Proteins

Year: 1998 PMID： 9399857 PMCID： PMC147177 DOI： 10.1093/nar/26.1.292

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

44 in total

1. Induction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation.

Authors: R W Gedrich; S T Bayley; D A Engel
Journal: J Virol Date: 1992-10 Impact factor: 5.103

Review 2. Adenovirus E1A targets key regulators of cell proliferation.

Authors: N Dyson; E Harlow
Journal: Cancer Surv Date: 1992

3. Ability of adenovirus 5 E1A proteins to suppress differentiation of BC3H1 myoblasts correlates with their binding to a 300 kDa cellular protein.

Authors: J S Mymryk; R W Lee; S T Bayley
Journal: Mol Biol Cell Date: 1992-10 Impact factor: 4.138

Review 4. Transcriptional and transforming activities of the adenovirus E1A proteins.

Authors: T Shenk; J Flint
Journal: Adv Cancer Res Date: 1991 Impact factor: 6.242

5. Inhibition of IFN-stimulated gene expression and IFN induction of cytolytic resistance to natural killer cell lysis correlate with E1A-p300 binding.

Authors: J M Routes; H Li; S T Bayley; S Ryan; D J Klemm
Journal: J Immunol Date: 1996-02-01 Impact factor: 5.422

6. Cyclic AMP signaling is required for function of the N-terminal and CR1 domains of adenovirus E1A in Saccharomyces cerevisiae.

Authors: M E Miller; D A Engel; M M Smith
Journal: Oncogene Date: 1995-10-19 Impact factor: 9.867

7. Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanism.

Authors: K E Boulukos; E B Ziff
Journal: Oncogene Date: 1993-02 Impact factor: 9.867

Review 8. Adenovirus E1a as a tumor-suppressor gene.

Authors: G Chinnadurai
Journal: Oncogene Date: 1992-07 Impact factor: 9.867

9. Regulation of MyoD gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein.

Authors: M Caruso; F Martelli; A Giordano; A Felsani
Journal: Oncogene Date: 1993-02 Impact factor: 9.867

10. Identification and analysis of a retinoblastoma binding motif in the replication protein of a plant DNA virus: requirement for efficient viral DNA replication.

Authors: Q Xie; P Suárez-López; C Gutiérrez
Journal: EMBO J Date: 1995-08-15 Impact factor: 11.598

1 in total

1. p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing.

Authors: M B Flinterman; J S Mymryk; P Klanrit; A F Yousef; S W Lowe; C Caldas; J Gäken; F Farzaneh; M Tavassoli
Journal: Oncogene Date: 2007-05-07 Impact factor: 9.867

1 in total