Literature DB >> 9399850

APC gene: database of germline and somatic mutations in human tumors and cell lines.

P Laurent-Puig1, C Béroud, T Soussi.   

Abstract

A database (http://perso.curie.fr/tsoussi ) is described, in which over 1000 mutations in the human APC gene of tumors (colon cancer predominantly) are compiled from the literature. It includes both molecular information about the mutations and clinical data about the patients. Software has been designed to analyse all this information in the database.

Entities:  

Mesh：

Year:  1998        PMID： 9399850      PMCID： PMC147178          DOI： 10.1093/nar/26.1.269

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  19 in total

1.  Attenuated familial adenomatous polyposis due to a mutation in the 3' part of the APC gene. A clue for understanding the function of the APC protein.

Authors:  W Friedl; S Meuschel; R Caspari; C Lamberti; S Krieger; M Sengteller; P Propping
Journal:  Hum Genet       Date:  1996-05       Impact factor: 4.132

2.  Somatic mutations of the APC gene in sporadic hepatoblastomas.

Authors:  H Oda; Y Imai; Y Nakatsuru; J Hata; T Ishikawa
Journal:  Cancer Res       Date:  1996-07-15       Impact factor: 12.701

3.  Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC.

Authors:  S J Laken; G M Petersen; S B Gruber; C Oddoux; H Ostrer; F M Giardiello; S R Hamilton; H Hampel; A Markowitz; D Klimstra; S Jhanwar; S Winawer; K Offit; M C Luce; K W Kinzler; B Vogelstein
Journal:  Nat Genet       Date:  1997-09       Impact factor: 38.330

4.  Phenotypic variability of familial adenomatous polyposis in 11 unrelated families with identical APC gene mutation.

Authors:  F M Giardiello; A J Krush; G M Petersen; S V Booker; M Kerr; L L Tong; S R Hamilton
Journal:  Gastroenterology       Date:  1994-06       Impact factor: 22.682

5.  Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma.

Authors:  S Nakatsuru; A Yanagisawa; S Ichii; E Tahara; Y Kato; Y Nakamura; A Horii
Journal:  Hum Mol Genet       Date:  1992-11       Impact factor: 6.150

6.  Novel germline APC gene mutation in a large familial adenomatous polyposis kindred displaying variable phenotypes.

Authors:  R J Scott; R van der Luijt; M Spycher; J L Mary; A Müller; T Hoppeler; M Haner; H Müller; S Martinoli; P L Brazzola
Journal:  Gut       Date:  1995-05       Impact factor: 23.059

7.  Familial adenomatous polyposis: desmoid tumours and lack of ophthalmic lesions (CHRPE) associated with APC mutations beyond codon 1444.

Authors:  R Caspari; S Olschwang; W Friedl; M Mandl; C Boisson; T Böker; A Augustin; M Kadmon; G Möslein; G Thomas
Journal:  Hum Mol Genet       Date:  1995-03       Impact factor: 6.150

Review 8.  Mutations of the APC (adenomatous polyposis coli) gene.

Authors:  H Nagase; Y Nakamura
Journal:  Hum Mutat       Date:  1993       Impact factor: 4.878

9.  Mutations of the APC gene occur during early stages of gastric adenoma development.

Authors:  G Tamura; C Maesawa; Y Suzuki; H Tamada; M Satoh; S Ogasawara; M Kashiwaba; R Satodate
Journal:  Cancer Res       Date:  1994-03-01       Impact factor: 12.701

10.  Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene.

Authors:  D R Davies; J G Armstrong; N Thakker; K Horner; S P Guy; T Clancy; P Sloan; V Blair; C Dodd; T W Warnes
Journal:  Am J Hum Genet       Date:  1995-11       Impact factor: 11.025
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  40 in total

1.  Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection.

Authors:  H Huang; H Fujii; A Sankila; B M Mahler-Araujo; M Matsuda; G Cathomas; H Ohgaki
Journal:  Am J Pathol       Date:  1999-12       Impact factor: 4.307

2.  Inherited colorectal cancer syndromes.

Authors:  Robert Gryfe
Journal:  Clin Colon Rectal Surg       Date:  2009-11

3.  DNA copy number changes in Schistosoma-associated and non-Schistosoma-associated bladder cancer.

Authors:  W El-Rifai; D Kamel; M L Larramendy; S Shoman; Y Gad; S Baithun; M El-Awady; S Eissa; H Khaled; S Soloneski; M Sheaff; S Knuutila
Journal:  Am J Pathol       Date:  2000-03       Impact factor: 4.307

Review 4.  Diseases of Wnt signaling.

Authors:  Mark L Johnson; Nalini Rajamannan
Journal:  Rev Endocr Metab Disord       Date:  2006-06       Impact factor: 6.514

5.  Somatic mutations of the APC gene in primary breast cancers.

Authors:  K Furuuchi; M Tada; H Yamada; A Kataoka; N Furuuchi; J Hamada; M Takahashi; S Todo; T Moriuchi
Journal:  Am J Pathol       Date:  2000-06       Impact factor: 4.307

Review 6.  Familial Colorectal Cancer: Understanding the Alphabet Soup.

Authors:  Matthew D Giglia; Daniel I Chu
Journal:  Clin Colon Rectal Surg       Date:  2016-09

7.  Serum Levels of Glycoproteins are Elevated in Patients with Ovarian Cancer.

Authors:  Vikram Thakkar; Purvi Patel; Neelam Prajapati; Ranjit Kaur; Mukesh Nandave
Journal:  Indian J Clin Biochem       Date:  2013-09-08

Review 8.  Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families.

Authors:  Christopher D Heinen
Journal:  Mutat Res       Date:  2009-09-17       Impact factor: 2.433

9.  Familial adenomatous polyposis patients without an identified APC germline mutation have a severe phenotype.

Authors:  M L Bisgaard; R Ripa; A L Knudsen; S Bülow
Journal:  Gut       Date:  2004-02       Impact factor: 23.059

10.  Detection of P53 mutations in different cancer types is improved by cDNA sequencing.

Authors:  Sylwester Piaskowski; Izabela Zawlik; Malgorzata Szybka; Dominika Kulczycka-Wojdala; Ewelina Stoczynska-Fidelus; Michal Bienkowski; Tadeusz Robak; Renata Kusinska; Dorota Jesionek-Kupnicka; Radzislaw Kordek; Piotr Rieske; Pawel P Liberski
Journal:  Oncol Lett       Date:  2010-07-01       Impact factor: 2.967
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