Literature DB >> 9399836

p53 gene mutation: software and database.

C Béroud1, T Soussi.   

Abstract

A large number of different mutations in the p53 tumor suppressor gene have been identified in all types of cancer. As of October, 1997, this database (http:// perso.curie.fr/tsoussi ) contained >7500 mutations. Such a substantial increase since our previous reports should enable epidemiological analyses which were not previously possible. In order to analyse these new data, the UMD software has been improved. A new Web version of the UMD software enables online analysis of the database. The present report describes various improvements since the last release of the database.

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Year:  1998        PMID： 9399836      PMCID： PMC147206          DOI： 10.1093/nar/26.1.200

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  18 in total

1.  TP53 mutations and breast cancer prognosis: particularly poor survival rates for cases with mutations in the zinc-binding domains.

Authors:  A L Børresen; T I Andersen; J E Eyfjörd; R S Cornelis; S Thorlacius; A Borg; U Johansson; C Theillet; S Scherneck; S Hartman
Journal:  Genes Chromosomes Cancer       Date:  1995-09       Impact factor: 5.006

Review 2.  TP53 tumor suppressor gene: a model for investigating human mutagenesis.

Authors:  C Caron de Fromentel; T Soussi
Journal:  Genes Chromosomes Cancer       Date:  1992-01       Impact factor: 5.006

3.  Database and software for the analysis of mutations in the human p53 gene.

Authors:  N F Cariello; L Cui; C Beroud; T Soussi
Journal:  Cancer Res       Date:  1994-08-15       Impact factor: 12.701

4.  Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.

Authors:  Y Cho; S Gorina; P D Jeffrey; N P Pavletich
Journal:  Science       Date:  1994-07-15       Impact factor: 47.728

5.  A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

Authors:  D E Brash; J A Rudolph; J A Simon; A Lin; G J McKenna; H P Baden; A J Halperin; J Pontén
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-15       Impact factor: 11.205

6.  Software and database for the analysis of mutations in the human FBN1 gene.

Authors:  G Collod; C Béroud; T Soussi; C Junien; C Boileau
Journal:  Nucleic Acids Res       Date:  1996-01-01       Impact factor: 16.971

7.  p53 point mutation and survival in colorectal cancer patients.

Authors:  H S Goh; J Yao; D R Smith
Journal:  Cancer Res       Date:  1995-11-15       Impact factor: 12.701

Review 8.  Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene?

Authors:  N Dumaz; A Stary; T Soussi; L Daya-Grosjean; A Sarasin
Journal:  Mutat Res       Date:  1994-05-01       Impact factor: 2.433

9.  Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy.

Authors:  J Bergh; T Norberg; S Sjögren; A Lindgren; L Holmberg
Journal:  Nat Med       Date:  1995-10       Impact factor: 53.440

10.  Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

Authors:  K Ory; Y Legros; C Auguin; T Soussi
Journal:  EMBO J       Date:  1994-08-01       Impact factor: 11.598
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  25 in total

1.  Comparison of p53 mutations induced by PAH o-quinones with those caused by anti-benzo[a]pyrene diol epoxide in vitro: role of reactive oxygen and biological selection.

Authors:  Yu-Min Shen; Andrea B Troxel; Srilakshmi Vedantam; Trevor M Penning; Jeffrey Field
Journal:  Chem Res Toxicol       Date:  2006-11       Impact factor: 3.739

2.  Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis.

Authors:  Hamdiye Erdal; Maria Berndtsson; Juan Castro; Ulf Brunk; Maria C Shoshan; Stig Linder
Journal:  Proc Natl Acad Sci U S A       Date:  2004-12-23       Impact factor: 11.205

3.  Stool-based DNA testing, a new noninvasive method for colorectal cancer screening, the first report from Iran.

Authors:  Mohammad Reza Abbaszadegan; Alireza Tavasoli; Arash Velayati; Hamid Reza Sima; Hassan Vosooghinia; Mehdi Farzadnia; Hamid Asadzedeh; Mehran Gholamin; Ezzat Dadkhah; Azadeh Aarabi
Journal:  World J Gastroenterol       Date:  2007-03-14       Impact factor: 5.742

4.  INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

Authors:  C A Schmitt; M E McCurrach; E de Stanchina; R R Wallace-Brodeur; S W Lowe
Journal:  Genes Dev       Date:  1999-10-15       Impact factor: 11.361

5.  Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers.

Authors:  Y Takagi; M Futamura; K Yamaguchi; S Aoki; T Takahashi; S Saji
Journal:  Gut       Date:  2000-08       Impact factor: 23.059

6.  Enhanced retrieval of DNA from human fecal samples results in improved performance of colorectal cancer screening test.

Authors:  Duncan Whitney; Joel Skoletsky; Kent Moore; Kevin Boynton; Lisa Kann; Randall Brand; Sapna Syngal; Michael Lawson; Anthony Shuber
Journal:  J Mol Diagn       Date:  2004-11       Impact factor: 5.568

7.  The spectrum of p53 mutations in colorectal adenomas differs from that in colorectal carcinomas.

Authors:  X P Hao; I M Frayling; J G Sgouros; M Q Du; T C Willcocks; I C Talbot; I P M Tomlinson
Journal:  Gut       Date:  2002-06       Impact factor: 23.059

Review 8.  Somatic TP53 Mutations in the Era of Genome Sequencing.

Authors:  Pierre Hainaut; Gerd P Pfeifer
Journal:  Cold Spring Harb Perspect Med       Date:  2016-11-01       Impact factor: 6.915

9.  The pattern of p53 mutations caused by PAH o-quinones is driven by 8-oxo-dGuo formation while the spectrum of mutations is determined by biological selection for dominance.

Authors:  Jong-Heum Park; Stacy Gelhaus; Srilakshmi Vedantam; Andrea L Oliva; Abhita Batra; Ian A Blair; Andrea B Troxel; Jeffrey Field; Trevor M Penning
Journal:  Chem Res Toxicol       Date:  2008-05       Impact factor: 3.739

10.  Identification of a novel germ-line mutation in the TP53 gene in a Mexican family with Li-Fraumeni syndrome.

Authors:  Lucia Taja-Chayeb; Silvia Vidal-Millán; Olga Gutiérrez-Hernández; Catalina Trejo-Becerril; Enrique Pérez-Cárdenas; Alma Chávez-Blanco; Erick de la Cruz-Hernández; Alfonso Dueñas-González
Journal:  World J Surg Oncol       Date:  2009-12-17       Impact factor: 2.754
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