Literature DB >> 9395252

Expression of prostaglandin EP2 receptor mRNA in the rat spinal cord.

T Kawamura1, T Yamauchi, M Koyama, T Maruyama, T Akira, N Nakamura.   

Abstract

RT-PCR and an in situ hybridization analyses demonstrated expression of prostaglandin EP2 receptor mRNA in the subfield of the dorsal horn of the rat spinal cord. The intensive signals from the cells labeled with digoxigenin-11-dUTP were scattered through this region and they corresponded to neurons. EP2 receptor-mediated signal transduction is expected to play roles in modulating some neuronal functions such as transmission of nociceptive reaction or motor reflex.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9395252     DOI： 10.1016/s0024-3205(97)00884-9

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  6 in total

1.  Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.

Authors:  Christian Brenneis; Ovidiu Coste; Kai Altenrath; Carlo Angioni; Helmut Schmidt; Claus-Dieter Schuh; Dong Dong Zhang; Marina Henke; Andreas Weigert; Bernhard Brüne; Barry Rubin; Rolf Nusing; Klaus Scholich; Gerd Geisslinger
Journal:  J Biol Chem       Date:  2010-11-12       Impact factor: 5.157

2.  Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype.

Authors:  Heiko Reinold; Seifollah Ahmadi; Ulrike B Depner; Beate Layh; Cornelia Heindl; May Hamza; Andreas Pahl; Kay Brune; Shuh Narumiya; Ulrike Müller; Hanns Ulrich Zeilhofer
Journal:  J Clin Invest       Date:  2005-03       Impact factor: 14.808

3.  Spinal prostaglandins are involved in the development but not the maintenance of inflammation-induced spinal hyperexcitability.

Authors:  E Vasquez; K J Bär; A Ebersberger; B Klein; H Vanegas; H G Schaible
Journal:  J Neurosci       Date:  2001-11-15       Impact factor: 6.167

4.  Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity.

Authors:  Tatsuro Kohno; Haibin Wang; Fumimasa Amaya; Gary J Brenner; Jen-Kun Cheng; Ru-Rong Ji; Clifford J Woolf
Journal:  J Neurosci       Date:  2008-04-23       Impact factor: 6.167

5.  Role of prostaglandins in spinal transmission of the exercise pressor reflex in decerebrated rats.

Authors:  A J Stone; S W Copp; M P Kaufman
Journal:  Neuroscience       Date:  2014-07-05       Impact factor: 3.590

6.  Advancing our understanding of the mechanisms and mediators underlying pain and inflammation.

Authors:  Hermann O Handwerker
Journal:  Clin Drug Investig       Date:  2007-12       Impact factor: 2.859
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.