Literature DB >> 939399

Effect of liquid diet on serum protein binding and prednisolone concentrations after oral prednisone.

M Uribe, S W Schalm, W H Summerskill, V L Go.   

Abstract

After prednisone (two 5 mg tablets) was given to each of six normal volunteers with water or with a liquid meal, standard pharmacokinetic parameters of prednisolone metabolism were similar, except that peak serum prednisolone concentrations occurred later after the meal. We conclude that prednisone can be given with a meal without significantly affecting the metabolism of prednisone or prednisolone.

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Year:  1976        PMID: 939399

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  8 in total

1.  Variation in plasma prednisolone concentrations in renal transplant recipients given enteric-coated prednisolone.

Authors:  R G Henderson; T Wheatley; J English; J Chakraborty; V Marks
Journal:  Br Med J       Date:  1979-06-09

Review 2.  Pharmacokinetics and bioavailability of prednisone and prednisolone in healthy volunteers and patients: a review.

Authors:  J G Gambertoglio; W J Amend; L Z Benet
Journal:  J Pharmacokinet Biopharm       Date:  1980-02

3.  Oral prednisone for chronic active liver disease: dose responses and bioavailability studies.

Authors:  M Uribe; S W Schalm; W H Summerskill; V L Go
Journal:  Gut       Date:  1978-12       Impact factor: 23.059

4.  Effect of food on the absorption and pharmacokinetics of prednisolone from enteric-coated tablets.

Authors:  S M Al-Habet; H J Rogers
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

5.  Comparative serum prednisone and prednisolone concentrations following administration to patients with chronic active liver disease.

Authors:  M Uribe; W H Summerskill; V L Go
Journal:  Clin Pharmacokinet       Date:  1982 Sep-Oct       Impact factor: 6.447

6.  Plasma prednisolone studies in rheumatic patients.

Authors:  M Hayes; A F Alam; F E Bruckner; S M Doherty; A Myles; J English; V Marks; J Chakraborty
Journal:  Ann Rheum Dis       Date:  1983-04       Impact factor: 19.103

Review 7.  Corticosteroid pharmacokinetics in liver disease.

Authors:  M Uribe; V L Go
Journal:  Clin Pharmacokinet       Date:  1979 May-Jun       Impact factor: 6.447

8.  Plasma prednisolone measurements in renal transplant patients.

Authors:  J Chakraborty
Journal:  Ulster Med J       Date:  1981
  8 in total

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