Literature DB >> 9390340

Human herpesvirus 6 infection associated with anticonvulsant hypersensitivity syndrome and reactive haemophagocytic syndrome.

V Descamps1, F Bouscarat, S Laglenne, E Aslangul, B Veber, D Descamps, J L Saraux, M J Grange, M Grossin, E Navratil, B Crickx, S Belaich.   

Abstract

Viral infections are thought to play a part in some cutaneous drug reactions. Human herpesvirus 6 (HHV6), which is the agent of exanthema subitum (sixth disease), has never been implicated in a drug reaction. We report a patient with severe phenobarbital-induced anticonvulsant hypersensitivity syndrome in whom a fulminant haemophagocytic syndrome was associated with HHV6 infection. We discuss the possible role of HHV6 in this reactive condition.

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Year:  1997        PMID： 9390340     DOI： 10.1111/j.1365-2133.1997.tb03795.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN： 0007-0963            Impact factor:   9.302


  24 in total

1.  ATL-like marked atypical lymphocytosis associated with drug-induced hypersensitivity syndrome and human herpesvirus-6 reactivation.

Authors:  Tomonori Nakazato; Kazuhito Suzuki; Ai Mihara; Yukinari Sanada; Yoshinobu Aisa; Tsunayuki Kakimoto
Journal:  Int J Hematol       Date:  2009-11-25       Impact factor: 2.490

Review 2.  Fever, rash, and systemic symptoms: understanding the role of virus and HLA in severe cutaneous drug allergy.

Authors:  Rebecca Pavlos; Simon Mallal; David Ostrov; Yuri Pompeu; Elizabeth Phillips
Journal:  J Allergy Clin Immunol Pract       Date:  2014 Jan-Feb

Review 3.  Anticonvulsant hypersensitivity syndrome in children: incidence, prevention and management.

Authors:  Alberto Verrotti; Daniela Trotta; Carmela Salladini; Francesco Chiarelli
Journal:  CNS Drugs       Date:  2002       Impact factor: 5.749

Review 4.  Skin manifestations of drug allergy.

Authors:  Michael R Ardern-Jones; Peter S Friedmann
Journal:  Br J Clin Pharmacol       Date:  2011-05       Impact factor: 4.335

5.  Drug Reaction, Eosinophilia and Systemic Symptoms (DRESS) syndrome secondary to allopurinol with early lymphadenopathy and symptom relapse.

Authors:  Rhiannon Turney; Jordan Peter Skittrall; Joseph Donovan; Daniel Agranoff
Journal:  BMJ Case Rep       Date:  2015-10-05

6.  Neutralizing antibody responses to human herpesviruses 6 and 7 do not cross-react with each other, and maternal neutralizing antibodies contribute to sequential infection with these viruses in childhood.

Authors:  Mariko Yoshida; Sadayoshi Torigoe; Kumiko Ikeue; Masao Yamada
Journal:  Clin Diagn Lab Immunol       Date:  2002-03

Review 7.  Laboratory and clinical aspects of human herpesvirus 6 infections.

Authors:  Henri Agut; Pascale Bonnafous; Agnès Gautheret-Dejean
Journal:  Clin Microbiol Rev       Date:  2015-04       Impact factor: 26.132

8.  Sulfasalazine-induced hypersensitivity syndrome and hemophagocytic syndrome associated with reactivation of Epstein-Barr virus.

Authors:  Atsushi Komatsuda; Yohsuke Okamoto; Takashi Hatakeyama; Hideki Wakui; Ken-ichi Sawada
Journal:  Clin Rheumatol       Date:  2007-10-19       Impact factor: 2.980

9.  Drug hypersensitivity to previously tolerated phenytoin by carbamazepine-induced DRESS syndrome.

Authors:  Cheol-Woo Kim; Gwang-Seong Choi; Chang-Ho Yun; Deok-In Kim
Journal:  J Korean Med Sci       Date:  2006-08       Impact factor: 2.153

10.  Copy numbers of telomeric repeat sequences of human herpesvirus 6B in clinical isolates: possibility of mixed infections.

Authors:  Yuri Kato; Masaru Ihira; Mami Umeda; Yuki Higashimoto; Yoshiki Kawamura; Masahiro Ohashi; Junichi Ishi; Tetsushi Yoshikawa
Journal:  J Clin Microbiol       Date:  2013-11-13       Impact factor: 5.948
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