Literature DB >> 9389984

Origin of hepatocellular carcinoma recurring after allotransplantation revealed by microsatellite analysis.

H Pfeiffer1, C Ortmann, A Klein, B Brinkmann.   

Abstract

A hepatocellular carcinoma was resected from a liver allotransplant after the patient's original organ had been removed because of a liver carcinoma. DNA analysis was performed to explore the origin of the carcinoma cells. DNA extracted from the carcinoma tissue, from the carcinoma free liver tissue, and from other cells of the recipient underwent polymerase chain reaction amplification for seven microsatellite systems and the X-Y amelogenin system. The allelic pattern from the carcinoma tissue was identical with that from the patient and differed from the DNA profile of the liver tissue. The result confirmed the assumption that the carcinoma tissue had originated from the patient and not from the donor.

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Year:  1997        PMID： 9389984      PMCID： PMC500180          DOI： 10.1136/jcp.50.9.792

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  11 in total

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Authors:  D P Jackson; F A Lewis; G R Taylor; A W Boylston; P Quirke
Journal:  J Clin Pathol       Date:  1990-06       Impact factor: 3.411

2.  Structural variation in the alleles of a short tandem repeat system at the human alpha fibrinogen locus.

Authors:  M D Barber; B J McKeown; B H Parkin
Journal:  Int J Legal Med       Date:  1996       Impact factor: 2.686

3.  Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material.

Authors:  P S Walsh; D A Metzger; R Higuchi
Journal:  Biotechniques       Date:  1991-04       Impact factor: 1.993

4.  Population data and forensic efficiency values for the STR systems HumVWA, HumMBP and HumFABP.

Authors:  A Möller; P Wiegand; C Grüschow; S A Seuchter; M P Baur; B Brinkmann
Journal:  Int J Legal Med       Date:  1994       Impact factor: 2.686

5.  Ancient bone DNA amplified.

Authors:  E Hagelberg; B Sykes; R Hedges
Journal:  Nature       Date:  1989-11-30       Impact factor: 49.962

Review 6.  Repetitive deoxyribonucleic acid (DNA) and human genome variation--a concise review relevant to forensic biology.

Authors:  J C Fowler; L A Burgoyne; A C Scott; H W Harding
Journal:  J Forensic Sci       Date:  1988-09       Impact factor: 1.832

7.  Morphological detection of X- and Y-chromosomes in smears and paraffin-embedded tissues using a non-isotopic in situ hybridization technique (NISH).

Authors:  P Betz; G Baretton; J Tübel; A Nerlich; W Eisenmenger
Journal:  Int J Legal Med       Date:  1994       Impact factor: 2.686

8.  Influence of age on the outcome of 500 autologous bone marrow transplant procedures for hematologic malignancies.

Authors:  C R Kusnierz-Glaz; P G Schlegel; R M Wong; J R Schriber; N J Chao; M D Amylon; W W Hu; R S Negrin; Y Lee; K G Blume; G D Long
Journal:  J Clin Oncol       Date:  1997-01       Impact factor: 44.544

9.  Different types of structural variation in STRs: HumFES/FPS, HumVWA and HumD21S11.

Authors:  A Möller; E Meyer; B Brinkmann
Journal:  Int J Legal Med       Date:  1994       Impact factor: 2.686

10.  DNA typing and genetic mapping with trimeric and tetrameric tandem repeats.

Authors:  A Edwards; A Civitello; H A Hammond; C T Caskey
Journal:  Am J Hum Genet       Date:  1991-10       Impact factor: 11.025
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  1 in total

Review 1.  Donor-transmitted malignancy in a liver transplant recipient: a case report and review of literature.

Authors:  Brian Kim; Tinsay Woreta; Po-Hung Chen; Berkeley Limketkai; Andrew Singer; Nabil Dagher; Andrew Cameron; Ming-Tseh Lin; Ihab Kamel; Ahmet Gurakar
Journal:  Dig Dis Sci       Date:  2012-12-16       Impact factor: 3.199
  1 in total

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