Literature DB >> 9389946

Are reported stress and coping style associated with frequent recurrence of genital herpes?

L Cassidy1, J Meadows, J Catalán, S Barton.   

Abstract

OBJECTIVES: This paper reports on the cross sectional data from the longitudinal study examining the impact of genital herpes simplex virus (HSV) infection on quality of life. In particular the report sought to study the relation between recurrence of genital HSV and coping style, mood, personality, and quality of life, among other factors. SETTING AND
SUBJECTS: 116 patients with a known history of genital herpes simplex infection attending the Department of Genitourinary Medicine at Chelsea and Westminster Hospital.
METHODS: Psychosocial factors (stress, anxiety, depression, health locus of control, personality, social support, coping skills, and quality of life) and the reported frequency of genital herpes episodes were measured using self administered questionnaires designed to examine the relation between psychosocial status and the frequency of genital HSV episodes.
RESULTS: The number of recurrences reported by patients was significantly related to the style of coping skills used. Higher recurrences were less likely to use problem focused coping skills of planning and active coping, and the emotion focused coping skills of positive reinterpretation and growth. There was a significant difference in the number of patients who believed that psychological stress was related to the number of recurrences they experienced. This belief was related to neuroticism on the Eysenck Personality Questionnaire scale, and not to any of the other measures investigated.
CONCLUSION: The findings suggest that it is the way individuals cope, and their personality characteristics rather than actual levels of psychological stress, that influence their belief in a link between recurrent genital HSV and stress. HSV may become the focus of existing concerns and be viewed as the physical manifestation of stress.

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Mesh:

Year:  1997        PMID: 9389946      PMCID: PMC1195854          DOI: 10.1136/sti.73.4.263

Source DB:  PubMed          Journal:  Genitourin Med        ISSN: 0266-4348


  19 in total

1.  Psychological factors in recurrent genital herpes infection: stress, coping style, social support, emotional dysfunction, and symptom recurrence.

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Authors:  L Corey; H G Adams; Z A Brown; K K Holmes
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  8 in total

1.  Genital herpes: Heisenberg revisited.

Authors:  D Goldmeier
Journal:  Sex Transm Infect       Date:  1998-06       Impact factor: 3.519

2.  HSV type specific antibody tests: patients are ready, are clinicians?

Authors:  R L Ashley; L Corey
Journal:  Genitourin Med       Date:  1997-08

3.  Independent Cis-Regulatory Modules within the Herpes Simplex Virus 1 Infected Cell Protein 0 (ICP0) Promoter Are Transactivated by Krüppel-like Factor 15 and Glucocorticoid Receptor.

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4.  Transactivation of Herpes Simplex Virus 1 (HSV-1) Infected Cell Protein 4 Enhancer by Glucocorticoid Receptor and Stress-Induced Transcription Factors Requires Overlapping Krüppel-Like Transcription Factor 4/Sp1 Binding Sites.

Authors:  Jeffery B Ostler; Prasanth Thunuguntla; Bailey Y Hendrickson; Clinton Jones
Journal:  J Virol       Date:  2021-01-28       Impact factor: 5.103

5.  Specific Akt Family Members Impair Stress-Mediated Transactivation of Viral Promoters and Enhance Neuronal Differentiation: Important Functions for Maintaining Latency.

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Authors:  Mathijs H Brentjens; Kimberly A Yeung-Yue; Patricia C Lee; Stephen K Tyring
Journal:  Pharmacoeconomics       Date:  2003       Impact factor: 4.981

7.  Regulation of neurotropic herpesvirus productive infection and latency-reactivation cycle by glucocorticoid receptor and stress-induced transcription factors.

Authors:  Jeffery B Ostler; Laximan Sawant; Kelly Harrison; Clinton Jones
Journal:  Vitam Horm       Date:  2021-07-21       Impact factor: 2.247

8.  Stress Induced Transcription Factors Transactivate the Herpes Simplex Virus 1 Infected Cell Protein 27 (ICP27) Transcriptional Enhancer.

Authors:  Jeffery B Ostler; Clinton Jones
Journal:  Viruses       Date:  2021-11-17       Impact factor: 5.048

  8 in total

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