| Literature DB >> 9388773 |
J L Rinkenberger1, S J Korsmeyer.
Abstract
Apoptosis research has accelerated with the discovery of genes within a common cell death pathway and evidence for their inter-relationship. Breakthroughs include insights into the mechanism of action of the Bcl-2 family, caspases and their targets, and death receptor complexes. Deregulation of apoptosis is evident in tumors and viral infection, as well as in autoimmune disease, immunodeficiency, neurodegeneration, and infertility.Entities:
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Year: 1997 PMID: 9388773 DOI: 10.1016/s0959-437x(97)80004-4
Source DB: PubMed Journal: Curr Opin Genet Dev ISSN: 0959-437X Impact factor: 5.578