| Literature DB >> 9387894 |
S E Snyder1, J Li, S R Salton.
Abstract
The vgf gene encodes a neuronal secretory-peptide precursor that is rapidly induced by neurotrophic growth factors and by depolarization in vitro. To gain insight into the possible functions and regulation of VGF in vivo, we characterized the expression of VGF messenger RNA (mRNA) by in situ hybridization, during development and in adult brain, and directly compared it to the distributions of mRNAs encoding neurotrophin receptors TrkA, TrkB, and TrkC. Overlap in VGF and trk mRNA expression exists, and though no trk mRNA was exclusively colocalized with VGF message, the best correlation was found between the distributions of the VGF and trkB kinase mRNAs.Entities:
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Year: 1997 PMID： 9387894 DOI： 10.1016/s0169-328x(97)00216-7
Source DB: PubMed Journal: Brain Res Mol Brain Res ISSN： 0169-328X