Literature DB >> 938721

A new analysis for membrane noise. The integral spectrum.

L J DeFelice, B A Sokol.   

Abstract

A new method of random data analysis has been developed with special implications for membrane noise. The integral spectrometer uses overlapping broad-band filters of simple design, whose bandwidth increases linearly with center frequency. A random two-state process, which has a Lorentzian-shaped spectral density, results in an integral spectrum whose maximum value occurs at the mean frequency of the events, and which is symmetric about that frequency on a semilog plot. 1/f noise is flat and does not distort the symmetry on the frequency axis. The integral spectrum exchanges resolution on the frequency axis for accuracy in the amplitude. The expected statistical error in amplitude has been calculated for three types of membrane noise assuming finite data. The integral spectrum compares favorably with conventional spectral densities and may be a reasonable alternative for random data analysis.

Mesh:

Year:  1976        PMID: 938721      PMCID: PMC1334903          DOI: 10.1016/S0006-3495(76)85731-1

Source DB:  PubMed          Journal:  Biophys J        ISSN: 0006-3495            Impact factor:   4.033


  7 in total

1.  Conductance fluctuations in Ranvier nodes.

Authors:  R J van den Berg; J de Goede; A A Verveen
Journal:  Pflugers Arch       Date:  1975-10-16       Impact factor: 3.657

2.  Potassium and sodium current noise from squid axon membranes.

Authors:  L J DeFelice; E Wanke; F Conti
Journal:  Fed Proc       Date:  1975-04

3.  Fluctuation spectroscopy: determination of chemical reaction kinetics from the frequency spectrum of fluctuations.

Authors:  G Feher; M Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

Review 4.  Membrane noise.

Authors:  A A Verveen; L J DeFelice
Journal:  Prog Biophys Mol Biol       Date:  1974       Impact factor: 3.667

5.  Fluctuations and noise in kinetic systems. Application to K+ channels in the squid axon.

Authors:  Y D Chen; T L Hill
Journal:  Biophys J       Date:  1973-12       Impact factor: 4.033

6.  On the theory of ion transport across the nerve membrane. IV. Noise from the open-close kinetics of K + channels.

Authors:  T L Hill; Y D Chen
Journal:  Biophys J       Date:  1972-08       Impact factor: 4.033

7.  Inferences about membrane properties from electrical noise measurements.

Authors:  C F Stevens
Journal:  Biophys J       Date:  1972-08       Impact factor: 4.033

  7 in total
  3 in total

Review 1.  1/f noise in membranes.

Authors:  B Neumcke
Journal:  Biophys Struct Mech       Date:  1978-07-12

2.  Use of octave filters in the measurement of random noise spectral density.

Authors:  M W Strandberg
Journal:  Biophys J       Date:  1977-04       Impact factor: 4.033

3.  Comments on the analysis of membrane noise by the "integral spectrum" procedure.

Authors:  D Poussart
Journal:  Biophys J       Date:  1977-04       Impact factor: 4.033

  3 in total

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