Literature DB >> 9386350

The immunoregulatory effects of NK cells: the role of TGF-beta and implications for autoimmunity.

D A Horwitz1, J D Gray, K Ohtsuka, M Hirokawa, T Takahashi.   

Abstract

The cytotoxic activities of natural killer (NK) cells--important in innate immunity--have received considerable attention, but NK cells also regulate T- and B-cell functions as well as hematopoiesis. Here, David Horwitz and colleagues focus on the capacity of NK cells to regulate antibody production positively and negatively, and in particular on the role of NK-cell transforming growth factor beta (TGF-beta) in downregulation of B-cell activity.

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Year:  1997        PMID： 9386350     DOI： 10.1016/s0167-5699(97)01149-3

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  23 in total

Review 1.  Cytokines and systemic lupus erythematosus.

Authors:  G S Dean; J Tyrrell-Price; E Crawley; D A Isenberg
Journal:  Ann Rheum Dis       Date:  2000-04       Impact factor: 19.103

2.  Phenotyping of peripheral blood lymphocytes in adult coeliac disease.

Authors:  A Di Sabatino; E Bertrandi; M Casadei Maldini; F Pennese; F Proietti; G R Corazza
Journal:  Immunology       Date:  1998-12       Impact factor: 7.397

3.  Natural killer cell activity in families of patients with systemic lupus erythematosus: demonstration of a killing defect in patients.

Authors:  M R J Green; A S M Kennell; M J Larche; M H Seifert; D A Isenberg; M R Salaman
Journal:  Clin Exp Immunol       Date:  2005-07       Impact factor: 4.330

4.  Transforming growth factor-beta expression in human retinal pigment epithelial cells is enhanced by Toxoplasma gondii: a possible role in the immunopathogenesis of retinochoroiditis.

Authors:  C N Nagineni; B Detrick; J J Hooks
Journal:  Clin Exp Immunol       Date:  2002-05       Impact factor: 4.330

5.  Antibody to α4 integrin suppresses natural killer cells infiltration in central nervous system in experimental autoimmune encephalomyelitis.

Authors:  Yan Gan; Ruolan Liu; Wei Wu; Roberto Bomprezzi; Fu-Dong Shi
Journal:  J Neuroimmunol       Date:  2012-04-13       Impact factor: 3.478

6.  Interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) are necessary in the early stages of induction of CD4 and CD8 cytotoxic T cells by Mycobacterium leprae heat shock protein (hsp) 65 kD.

Authors:  M C Sasiain; S de la Barrera; S Fink; M Finiasz; M Alemán; M H Fariña; G Pizzariello; R Valdez
Journal:  Clin Exp Immunol       Date:  1998-11       Impact factor: 4.330

Review 7.  Cytokine networks in systemic lupus erythematosus.

Authors:  Hooi-Ming Lee; Hidehiko Sugino; Norihiro Nishimoto
Journal:  J Biomed Biotechnol       Date:  2010-04-15

8.  Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1.

Authors:  Malte Bachmann; Katharina Horn; Ina Rudloff; Itamar Goren; Martin Holdener; Urs Christen; Nicole Darsow; Klaus-Peter Hunfeld; Ulrike Koehl; Peter Kind; Josef Pfeilschifter; Peter Kraiczy; Heiko Mühl
Journal:  PLoS Pathog       Date:  2010-10-14       Impact factor: 6.823

9.  NK cells dysfunction in systemic lupus erythematosus: relation to disease activity.

Authors:  Ana Henriques; Luís Teixeira; Luís Inês; Tiago Carvalheiro; Ana Gonçalves; António Martinho; Maria Luísa Pais; José António Pereira da Silva; Artur Paiva
Journal:  Clin Rheumatol       Date:  2013-02-02       Impact factor: 2.980

10.  CD48-deficient mice have a pronounced defect in CD4(+) T cell activation.

Authors:  J González-Cabrero; C J Wise; Y Latchman; G J Freeman; A H Sharpe; H Reiser
Journal:  Proc Natl Acad Sci U S A       Date:  1999-02-02       Impact factor: 11.205
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