Literature DB >> 9385090

Survival trees with time-dependent covariates: application to estimating changes in the incubation period of AIDS.

P Bacchetti1, M R Segal.   

Abstract

Tree-structured methods for exploratory data analysis have previously been extended to right-censored survival data. We further extend these methods to allow for truncation and time-dependent covariates. We apply the new methods to a data set on incubation times of acquired immunodeficiency syndrome (AIDS), using calendar time as a time-dependent covariate. Contrary to expectation, we find that rates of progression to AIDS appear to be faster after August 1989 than before.

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Year:  1995        PMID: 9385090     DOI: 10.1007/bf00985256

Source DB:  PubMed          Journal:  Lifetime Data Anal        ISSN: 1380-7870            Impact factor:   1.588


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