Literature DB >> 938467

Activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in brains of adult and 7-day-old rats.

M M Sudjic, R Booth.   

Abstract

Rat brain contains 3-hydroxy-3-methylglutaryl-CoA reductase activity, but this enzyme is far more active in 7-day-old brain than in adult brain. This difference may partly explain why cholesterol biosynthesis is more rapid in growing than in adult rat brain.

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Year:  1976        PMID： 938467      PMCID： PMC1172736          DOI： 10.1042/bj1540559

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  5 in total

1.  Incorporation of C14 of acetate-1-C14 and pyruvate-2-C14 into brain cholesterol in the intact rat.

Authors:  P J McMILLAN; G W DOUGLAS; R A MORTENSEN
Journal:  Proc Soc Exp Biol Med       Date:  1957-12

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Diurnal variations in rat liver 3-hydroxy-3-methylglutaryl-Coenzyme A reductase activity in relation to feeding.

Authors:  K W Gregory; C Z Smith; R Booth
Journal:  Biochem J       Date:  1972-12       Impact factor: 3.857

4.  Regulation of sterol synthesis in developing brains of normal and jimpy mice.

Authors:  A A Kandutsch; S E Saucier
Journal:  Arch Biochem Biophys       Date:  1969-12       Impact factor: 4.013

Review 5.  Vulnerable periods of brain development. In: lipids, malnutrition & the developing brain.

Authors:  J Dobbing
Journal:  Ciba Found Symp       Date:  1971
  5 in total
  6 in total

1.  Cytosolic 3-hydroxy-3-methyl glutaryl coenzyme a synthase in rat brain: properties and developmental change.

Authors:  S N Shah
Journal:  Neurochem Res       Date:  1982-11       Impact factor: 3.996

2.  Relationship between changes in free cholesterol and pyrophosphomevalonate decarboxylase activity during myelination.

Authors:  C Marco; D Gonzalez-Pacanowska; A Linares; E Garcia-Peregrin
Journal:  Neurochem Res       Date:  1983-06       Impact factor: 3.996

3.  Activation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in homogenates of developing rat brain.

Authors:  W A Maltese; J J Volpe
Journal:  Biochem J       Date:  1979-08-15       Impact factor: 3.857

4.  Acetoacetate metabolism in rat brain. Development of acetoacetyl-coenzyme A deacylase and 3-hydroxy-3-methylglutaryl-coenzyme A synthase.

Authors:  T B Patel; J B Clark
Journal:  Biochem J       Date:  1978-12-15       Impact factor: 3.857

5.  3-Hydroxy-3-methylglutaryl-coenzyme A reductase in normal and dystrophic hamsters.

Authors:  M C Greenough; R J Boegman
Journal:  Biochem J       Date:  1982-03-01       Impact factor: 3.857

6.  Changes in sterol biosynthesis accompanying cessation of glial cell growth in serum-free medium.

Authors:  W A Maltese; B A Reitz; J J Volpe
Journal:  Biochem J       Date:  1980-11-15       Impact factor: 3.857
  6 in total

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