Literature DB >> 9384528

Fiber-derived butyrate and the prevention of colon cancer.

C A Hassig1, J K Tong, S L Schreiber.   

Abstract

Inhibition of the enzyme histone deacetylase by butyrate results in the direct transcriptional upregulation of the cyclin-dependent kinase inhibitor p21/Cip1/WAF1. We discuss a small-molecule-mediated signaling pathway to explain the suspected anti-colon-cancer properties of fiber-derived butyrate.

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Year:  1997        PMID： 9384528     DOI： 10.1016/s1074-5521(97)90111-3

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  13 in total

1.  Increased colonic luminal synthesis of butyric acid is associated with lowered colonic cell proliferation in piglets.

Authors:  C Lawrence Kien; Mary Schmitz-Brown; Travis Solley; Dayong Sun; Wendy L Frankel
Journal:  J Nutr       Date:  2006-01       Impact factor: 4.798

2.  Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1.

Authors:  Mark A Cuff; Daniel W Lambert; Soraya P Shirazi-Beechey
Journal:  J Physiol       Date:  2002-03-01       Impact factor: 5.182

3.  External control of Her2 expression and cancer cell growth by targeting a Ras-linked coactivator.

Authors:  Shinichi Asada; Yongmun Choi; Masaki Yamada; Shao-Chun Wang; Mien-Chie Hung; Jun Qin; Motonari Uesugi
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-19       Impact factor: 11.205

4.  Gene expression profile of butyrate-inhibited vascular smooth muscle cell proliferation.

Authors:  Kasturi Ranganna; Zivar Yousefipour; Frank M Yatsu; Shirlette G Milton; Barbara E Hayes
Journal:  Mol Cell Biochem       Date:  2003-12       Impact factor: 3.396

Review 5.  Regulation of jasmonate-mediated plant responses in arabidopsis.

Authors:  Alessandra Devoto; John G Turner
Journal:  Ann Bot       Date:  2003-07-18       Impact factor: 4.357

6.  ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate.

Authors:  Longchuan Bai; Juanita L Merchant
Journal:  Biochem Biophys Res Commun       Date:  2007-06-06       Impact factor: 3.575

7.  3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin.

Authors:  Namrata Bhatnagar; Xia Li; Yue Chen; Xudong Zhou; Scott H Garrett; Bin Guo
Journal:  Cancer Prev Res (Phila)       Date:  2009-05-26

8.  Inhibitory effect of small amounts of cellulose on colonic carcinogenesis with low-dose carcinogen.

Authors:  Satoru Iwane; Shigeyuki Nakaji; Masanori Ohta; Ken Tamura; Juichi Sakamoto; Akihiro Munakata; Kazuo Sugawara
Journal:  Dig Dis Sci       Date:  2002-06       Impact factor: 3.199

9.  Butyrate down-regulates CD44 transcription and liver colonisation in a highly metastatic human colon carcinoma cell line.

Authors:  M Barshishat; I Levi; D Benharroch; B Schwartz
Journal:  Br J Cancer       Date:  2002-11-18       Impact factor: 7.640

10.  Butyrate regulates E-cadherin transcription, isoform expression and intracellular position in colon cancer cells.

Authors:  M Barshishat; S Polak-Charcon; B Schwartz
Journal:  Br J Cancer       Date:  2000-01       Impact factor: 7.640
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