| Literature DB >> 9383478 |
Abstract
Many phosphatases require two metal ions for catalysis. New structural information on two serine/threonine phosphatases offers insight into how the metals contribute to catalysis. A comparison with the structures of protein tyrosine phosphatases, which do not use metal ions, shows that the only similarity at the active site is that of charge.Entities:
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Year: 1995 PMID： 9383478 DOI： 10.1016/1074-5521(95)90098-5
Source DB: PubMed Journal: Chem Biol ISSN： 1074-5521