Literature DB >> 9383373

Targeting the glycosaminoglycan-binding sites on proteins.

A D Lander1.   

Abstract

Sulfated glycosaminoglycans bind to a wide variety of proteins, and in so doing have important roles in diverse biological processes. Selective mimics or inhibitors of protein-glycosaminoglycan interactions could have broad application in biology and medicine.

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Year:  1994        PMID: 9383373     DOI: 10.1016/1074-5521(94)90043-4

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  5 in total

1.  Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.

Authors:  J F Talts; Z Andac; W Göhring; A Brancaccio; R Timpl
Journal:  EMBO J       Date:  1999-02-15       Impact factor: 11.598

2.  Synthesis, separation, and characterization of amphiphilic sulfated oligosaccharides enabled by reversed-phase ion pairing LC and LC-MS methods.

Authors:  Amanda M Fenner; Robert J Kerns
Journal:  Carbohydr Res       Date:  2011-09-24       Impact factor: 2.104

3.  The anticoagulant activation of antithrombin by heparin.

Authors:  L Jin; J P Abrahams; R Skinner; M Petitou; R N Pike; R W Carrell
Journal:  Proc Natl Acad Sci U S A       Date:  1997-12-23       Impact factor: 11.205

4.  Proteolytic degradation of intestinal mucosal extracellular matrix after lamina propria T cell activation.

Authors:  S L Pender; P Lionetti; S H Murch; N Wathan; T T MacDonald
Journal:  Gut       Date:  1996-08       Impact factor: 23.059

5.  Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway.

Authors:  Wei Cheng; Chia-Jen Tseng; Tom T C Lin; I Cheng; Hung-Wei Pan; Hey-Chi Hsu; Yu-May Lee
Journal:  Carcinogenesis       Date:  2008-04-15       Impact factor: 4.944

  5 in total

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