| Literature DB >> 9379881 |
W F den Dunnen1, B van der Lei, J M Schakenraad, I Stokroos, E Blaauw, H Bartels, A J Pennings, P H Robinson.
Abstract
The aim of this study was to compare the speed and quality of nerve regeneration after reconstruction using a biodegradable nerve guide or an autologous nerve graft. We evaluated nerve regeneration using light microscopy, transmission electron microscopy and morphometric analysis. Nerve regeneration across a short nerve gap, after reconstruction using a biodegradable nerve guide, is faster and qualitatively better, when compared with nerve reconstruction using an autologous nerve graft. Therefore, we conclude that in the case of a short nerve gap (1 cm), reconstruction should be carried out using a biodegradable nerve guide constructed of a copolymer of DL-lactide and epsilon-caprolactone.Entities:
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Year: 1996 PMID： 9379881 DOI： 10.1002/(SICI)1098-2752(1996)17:7<348::AID-MICR2>3.0.CO;2-C
Source DB: PubMed Journal: Microsurgery ISSN： 0738-1085 Impact factor: 2.425