[D.K. Beliaev's evolutionary concept--ten years later].

D.K. Belyaev's evolutionary concept is considered in terms of (1) experimental results obtained during studies on domestication mainly in recent years and (2) modern views on evolution under extreme conditions and the role of the hierarchic system of regulation of genetic expression in evolution. Changes in neuroendocrine regulation in the course of long-term domestication are characterized, and the morphogenetic role of hormones and neurotransmitters is discussed. The effects of selection on the rate of some developmental processes and the importance of the resultant heterochronias for the morphogenetic consequences of selection for behavior are described.