Literature DB >> 937811

Mammalian toxicity of helenalin, the toxic principle of Helenium microcephalum CD (smallhead sneezeweed).

D A Witzel, W Ivie, J W Dollahite.   

Abstract

Studies with smallhead sneezeweed (Helenium microcephalum DC) indicated that a sesquiterpene lactone, helenalin, is the only significant toxic constituent present. The oral median lethal dose of helenalin for 5 mammalian species was between 85 and 105 mg/kg.

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Year:  1976        PMID： 937811

Source DB:  PubMed          Journal:  Am J Vet Res        ISSN： 0002-9645            Impact factor:   1.156


  4 in total

1.  Toxicity of Parthenium hysterophorus L. to cattle and buffaloes.

Authors:  T R Narasimhan; M Ananth; M N Swamy; M R Babu; A Mangala; P V Rao
Journal:  Experientia       Date:  1977-10-15

2.  Phagocytosis by sheep alveolar macrophages: relationship between opsonin concentration and light emission in the presence of luminol.

Authors:  R L Ziprin
Journal:  Infect Immun       Date:  1978-03       Impact factor: 3.441

Review 3.  Emerging Anti-Mitotic Activities and Other Bioactivities of Sesquiterpene Compounds upon Human Cells.

Authors:  Alessandra Bosco; Roy M Golsteyn
Journal:  Molecules       Date:  2017-03-13       Impact factor: 4.411

Review 4.  An Overview of NRF2-Activating Compounds Bearing α,β-Unsaturated Moiety and Their Antioxidant Effects.

Authors:  Melford Chuka Egbujor; Brigitta Buttari; Elisabetta Profumo; Pelin Telkoparan-Akillilar; Luciano Saso
Journal:  Int J Mol Sci       Date:  2022-07-30       Impact factor: 6.208
  4 in total

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