Literature DB >> 93729

In vivo release of substance P in the cat substantia nigra.

R Michelot, V Leviel, Y Torrens, J Glowinski, A Chéramy.   

Abstract

Push-pull cannuale were implanted into the substantia nigra (SN) and the caudate nucleus (CN) of the cat to study the in vivo release of substance P (SP), using a radioimmunoassay and high pressure liquid chromatography (HPLC) analysis. The spontaneous release of SP could be detected in the SN and the CN. Potassium (50 mM) locally applied stimulated SP release in both structures. Furthermore an important evoked release of SP was observed in the SN during depolarization of striato-nigral SP fibers with potassium (50 mM) applied in the CN.

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Year:  1979        PMID： 93729     DOI： 10.1016/0304-3940(79)96103-2

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  5 in total

1.  Tissue levels and in vivo release of tachykinins and GABA in striatum and substantia nigra of rat brain after unilateral striatal dopamine denervation.

Authors:  N Lindefors; E Brodin; U Tossman; J Segovia; U Ungerstedt
Journal:  Exp Brain Res       Date:  1989       Impact factor: 1.972

2.  International Substance P Symposium. Dublin, April 27-29, 1983. Abstracts.

Authors: 
Journal:  Ir J Med Sci       Date:  1983       Impact factor: 1.568

3.  Properties of a 125I-substance P derivative binding to synaptosomes from various brain structures and the spinal cord of the rat.

Authors:  Y Torrens; J C Beaujouan; A Viger; J Glowinski
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1983-09       Impact factor: 3.000

4.  Synaptic connections of substance P-immunoreactive nerve terminals in the substantia nigra of the rat. A correlated light- and electron-microscopic study.

Authors:  P Somogyi; J V Priestley; A C Cuello; A D Smith; J P Bolam
Journal:  Cell Tissue Res       Date:  1982       Impact factor: 5.249

5.  The postsynaptic targets of substance P-immunoreactive terminals in the rat neostriatum with particular reference to identified spiny striatonigral neurons.

Authors:  J P Bolam; P N Izzo
Journal:  Exp Brain Res       Date:  1988       Impact factor: 1.972
  5 in total

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