T P Hull1, J H Bates. 1. Department of Ophthalmology, Summa Health System, Akron, OH, USA. Tomphull@AOL.com
Abstract
PURPOSE: To present evidence for a causal relation between optic neuritis and influenza vaccination. METHODS: Case report. In a 59-year-old woman with bilateral optic neuritis, neuro-ophthalmologic examination, magnetic resonance imaging, fluorescent treponemal antibody absorption test, antinuclear antibodies, and complete blood cell count and chemistry were performed. RESULTS: Our patient developed bilateral optic neuritis on two occasions, 1 year apart. No evidence of neuroretinitis, syphilis, or systemic lupus erythematosus was identified. Influenza vaccination was given 2 weeks before the onset of each episode. CONCLUSION: This case provides compelling clinical evidence that implicates influenza vaccination as a cause of optic neuritis.
PURPOSE: To present evidence for a causal relation between optic neuritis and influenza vaccination. METHODS: Case report. In a 59-year-old woman with bilateral optic neuritis, neuro-ophthalmologic examination, magnetic resonance imaging, fluorescent treponemal antibody absorption test, antinuclear antibodies, and complete blood cell count and chemistry were performed. RESULTS: Our patient developed bilateral optic neuritis on two occasions, 1 year apart. No evidence of neuroretinitis, syphilis, or systemic lupus erythematosus was identified. Influenza vaccination was given 2 weeks before the onset of each episode. CONCLUSION: This case provides compelling clinical evidence that implicates influenza vaccination as a cause of optic neuritis.
Authors: Sharon K Greene; Martin Kulldorff; Edwin M Lewis; Rong Li; Ruihua Yin; Eric S Weintraub; Bruce H Fireman; Tracy A Lieu; James D Nordin; Jason M Glanz; Roger Baxter; Steven J Jacobsen; Karen R Broder; Grace M Lee Journal: Am J Epidemiol Date: 2009-12-04 Impact factor: 4.897
Authors: William Huynh; Dennis J Cordato; Elias Kehdi; Lynette T Masters; Chris Dedousis Journal: J Clin Neurosci Date: 2008-10-30 Impact factor: 1.961