BACKGROUND: There are reports of increased reactions in HIV-1+ patients to ultraviolet light sometimes in association with medication. In addition, there are also reports of increased morbidity associated with radiation therapy in HIV-1+ patients. METHODS: Three HIV-1+ patients developed cutaneous toxic reactions to radiation therapy; two with Kaposi's sarcoma (KS) and one with non-Hodgkin's lymphoma. CONCLUSIONS: Although the mechanisms which resulted in these reactions are not clear, they may be related to depletion of endogenous scavengers and may be accentuated by the pattern of immune dysregulation present in HIV-1 disease.
BACKGROUND: There are reports of increased reactions in HIV-1+ patients to ultraviolet light sometimes in association with medication. In addition, there are also reports of increased morbidity associated with radiation therapy in HIV-1+ patients. METHODS: Three HIV-1+ patients developed cutaneous toxic reactions to radiation therapy; two with Kaposi's sarcoma (KS) and one with non-Hodgkin's lymphoma. CONCLUSIONS: Although the mechanisms which resulted in these reactions are not clear, they may be related to depletion of endogenous scavengers and may be accentuated by the pattern of immune dysregulation present in HIV-1 disease.
Authors: Filiberto Cedeno-Laurent; Minerva Gómez-Flores; Nora Mendez; Jesús Ancer-Rodríguez; Joseph L Bryant; Anthony A Gaspari; Jose R Trujillo Journal: J Int AIDS Soc Date: 2011-01-24 Impact factor: 5.396
Authors: Jens Kübler; Stefanie Kirschner; Linda Hartmann; Grit Welzel; Maren Engelhardt; Carsten Herskind; Marlon R Veldwijk; Christian Schultz; Manuela Felix; Gerhard Glatting; Patrick Maier; Frederik Wenz; Marc A Brockmann; Frank A Giordano Journal: Oncotarget Date: 2016-07-19