Literature DB >> 9371233

Synthesis of 5,6-dihydro-4-hydroxy-2-pyrones as HIV-1 protease inhibitors: the profound effect of polarity on antiviral activity.

S E Hagen1, J V Prasad, F E Boyer, J M Domagala, E L Ellsworth, C Gajda, H W Hamilton, L J Markoski, B A Steinbaugh, B D Tait, E A Lunney, P J Tummino, D Ferguson, D Hupe, C Nouhan, S J Gracheck, J M Saunders, S VanderRoest.   

Abstract

Entities:  

Mesh:

Substances:

Year:  1997        PMID: 9371233     DOI: 10.1021/jm970522y

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  5 in total

1.  Classification of HIV protease inhibitors on the basis of their antiviral potency using radial basis function neural networks.

Authors:  S J Patankar; P C Jurs
Journal:  J Comput Aided Mol Des       Date:  2003 Feb-Apr       Impact factor: 3.686

2.  Synthesis, antitumor activity, and mechanism of action of 6-acrylic phenethyl ester-2-pyranone derivatives.

Authors:  Sai Fang; Lei Chen; Miao Yu; Bao Cheng; Yongsheng Lin; Susan L Morris-Natschke; Kuo-Hsiung Lee; Qiong Gu; Jun Xu
Journal:  Org Biomol Chem       Date:  2015-04-28       Impact factor: 3.876

3.  α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells.

Authors:  Rui-Min Yang; Xiu-Lei Zhang; Li Wang; Jian-Ping Huang; Jing Yang; Yi-Jun Yan; Jian-Ying Luo; Xiang-Ting Wang; Sheng-Xiong Huang
Journal:  Nat Prod Bioprospect       Date:  2017-06-20

4.  Synthesis and Evaluations of "1,4-Triazolyl Combretacoumarins" and Desmethoxy Analogues.

Authors:  Tashrique A Khandaker; Jessica D Hess; Renato Aguilera; Graciela Andrei; Robert Snoeck; Dominique Schols; Padmanava Pradhan; Mahesh K Lakshman
Journal:  European J Org Chem       Date:  2019-08-07

5.  Violapyrones H and I, new cytotoxic compounds isolated from Streptomyces sp. associated with the marine starfish Acanthaster planci.

Authors:  Hee Jae Shin; Hwa-Sun Lee; Jong Seok Lee; Junho Shin; Min Ah Lee; Hyi-Seung Lee; Yeon-Ju Lee; Jieun Yun; Jong Soon Kang
Journal:  Mar Drugs       Date:  2014-05-30       Impact factor: 5.118

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.