| Literature DB >> 9370107 |
A Perea1, C Viñambres, F Clemente, M L Villanueva-Peñacarrillo, I Valverde.
Abstract
In rat adipocytes, GLP-1 (7-36) amide induced an increment in 2-deoxy-glucose uptake, which was additive to that of insulin. Furthermore, in rat fat, GLP-1 (7-36) amide provoked a rise in glycogen synthesis, glucose oxidation and utilization and lipogenesis, the increments being lower than those obtained with insulin. These data support the idea that GLP-1 exerts insulin-like effects on glucose metabolism in rat adipose tissue, as it does in rat hepatocytes and skeletal muscle, although with a lower potency than that of insulin.Entities:
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Year: 1997 PMID： 9370107 DOI： 10.1055/s-2007-979068
Source DB: PubMed Journal: Horm Metab Res ISSN： 0018-5043 Impact factor: 2.936