| Literature DB >> 9368915 |
S Seçkin1, N Alptekin, S Doğru-Abbasoğlu, N Koçak-Toker, G Toker, M Uysal.
Abstract
The effect of chronic stress (immobilization and cold) on hepatic and gastric thiobarbituric acid reactive substances (TBARS) and vitamin C levels were investigated in rats having long-term depletion of glutathione (GSH) by applying buthionine sulfoximine (BSO). GSH and vitamin C levels decreased and TBARS levels increased in the liver and stomach of rats subjected to stress. Long-term BSO administration along with stress caused no additional changes in these parameters. These results may indicate that long-term glutathione depletion did not potentiate stress-induced hepatic and gastric lipid peroxidation.Entities:
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Year: 1997 PMID: 9368915 DOI: 10.1006/phrs.1997.0204
Source DB: PubMed Journal: Pharmacol Res ISSN: 1043-6618 Impact factor: 7.658