BACKGROUND: To identify predictors of psychosocial adjustment for survivors of adult acute leukemia, the adaptation of 206 survivors (77% with acute myelogenous leukemia, and 23% with acute lymphocytic leukemia) treated on any of 13 Cancer and Leukemia Group B trials during the period 1971-1988 was examined. METHODS: Survivors (median age, 41 years) who were at least 1 year from completion of all treatment (median, 5 years) were interviewed by telephone about psychologic symptoms; social, sexual, and vocational function; and beliefs about control over health. Standardized psychologic instruments were used to evaluate survivors' responses. RESULTS: Most survivors adapted well; however, 14% were 1.5 standard deviations above normal on the Global Severity Index of the Brief Symptom Inventory. Predictors of greater psychologic distress included less education, younger age, anticipatory distress during chemotherapy treatment, and the combination of more medical problems after treatment with poorer family function. Anticipatory nausea and distress during chemotherapy predicted persistent visceral distress later, which occurred with reminders of treatment. Anticipatory vomiting predicted a greater tendency toward cancer-related intrusive thoughts and avoidance of reminders. CONCLUSIONS: Patients experiencing anticipatory distress during treatment who are younger and less educated should be monitored for depressive syndromes later.
BACKGROUND: To identify predictors of psychosocial adjustment for survivors of adult acute leukemia, the adaptation of 206 survivors (77% with acute myelogenous leukemia, and 23% with acute lymphocytic leukemia) treated on any of 13 Cancer and Leukemia Group B trials during the period 1971-1988 was examined. METHODS: Survivors (median age, 41 years) who were at least 1 year from completion of all treatment (median, 5 years) were interviewed by telephone about psychologic symptoms; social, sexual, and vocational function; and beliefs about control over health. Standardized psychologic instruments were used to evaluate survivors' responses. RESULTS: Most survivors adapted well; however, 14% were 1.5 standard deviations above normal on the Global Severity Index of the Brief Symptom Inventory. Predictors of greater psychologic distress included less education, younger age, anticipatory distress during chemotherapy treatment, and the combination of more medical problems after treatment with poorer family function. Anticipatory nausea and distress during chemotherapy predicted persistent visceral distress later, which occurred with reminders of treatment. Anticipatory vomiting predicted a greater tendency toward cancer-related intrusive thoughts and avoidance of reminders. CONCLUSIONS:Patients experiencing anticipatory distress during treatment who are younger and less educated should be monitored for depressive syndromes later.
Authors: Smita C Banerjee; Matthew J Matasar; Carma L Bylund; Steven Horwitz; Kara McLarney; Tomer Levin; Paul B Jacobsen; Patricia Parker; Alan Astrow; David W Kissane Journal: Transl Behav Med Date: 2015-06-02 Impact factor: 3.046
Authors: Suzanne C Danhauer; Gregory B Russell; Richard G Tedeschi; Michelle T Jesse; Tanya Vishnevsky; Kristin Daley; Suzanne Carroll; Kelli N Triplett; Lawrence G Calhoun; Arnie Cann; Bayard L Powell Journal: J Clin Psychol Med Settings Date: 2013-03
Authors: Patricia A Parker; Susan K Peterson; Isabelle Bedrosian; Melissa A Crosby; Yu Shen; Dalliah M Black; Gildy Babiera; Henry M Kuerer; Jun Ying; Wenli Dong; Scott B Cantor; Abenaa M Brewster Journal: Ann Surg Date: 2016-01 Impact factor: 12.969