Literature DB >> 9362093

Antimycobacterial activity of some 2,3-dianilinoquinoxaline derivatives.

K Waisser1, R Beckert, M Slosáfrek, J Janota.   

Abstract

The antimycobacterial activity of 2,3-dianilinoquinoxaline derivatives was studied and the substances were found to be mostly wide-spectrum antimycobacterial agents. Replacement of one nitrogen atom in the heterocycle for oxygen or sulfur was usually accompanied by loss of activity. The model structure for the study was the wide-spectrum antimycobacterial drug clofazimine.

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Year:  1997        PMID： 9362093

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  2 in total

1.  Activities of Quinoxaline, Nitroquinoxaline, and [1,2,4]Triazolo[4,3-a]quinoxaline Analogs of MMV007204 against Schistosoma mansoni.

Authors:  Stefan L Debbert; Mikaela J Hintz; Christian J Bell; Kenya R Earl; Grant E Forsythe; Cécile Häberli; Jennifer Keiser
Journal:  Antimicrob Agents Chemother       Date:  2021-02-17       Impact factor: 5.191

2.  Orally active antischistosomal early leads identified from the open access malaria box.

Authors:  Katrin Ingram-Sieber; Noemi Cowan; Gordana Panic; Mireille Vargas; Nuha R Mansour; Quentin D Bickle; Timothy N C Wells; Thomas Spangenberg; Jennifer Keiser
Journal:  PLoS Negl Trop Dis       Date:  2014-01-09
  2 in total

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