Literature DB >> 9361354

MR assessment of red marrow distribution and composition in the proximal femur: correlation with clinical and laboratory parameters.

B C Vande Berg1, F E Lecouvet, P Moysan, B Maldague, J Jamart, J Malghem.   

Abstract

OBJECTIVE: To correlate the MR appearance of the proximal femur marrow with clinical and blood parameters. DESIGN AND PATIENTS: The proportion of the femoral neck surface area occupied by red marrow was determined on T1-weighted magnetic resonance (MR) images of the hip in a series of 120 subjects, aged from 15 to 75 years, with ten females and ten males per decade, and correlated with clinical data. This parameter and the bulk T1 values of femoral red marrow were determined in 30 other subjects 25-46 years of age and correlated with their blood parameters.
RESULTS: In the series of 120 subjects, the proportion of red marrow surface area decreased with age (P < 10(-4)) and was higher in female than male subjects (P < 10(-4)). Within each decade, the proportion of red marrow surface area was higher in females than in males between 25 and 65 years but neither before 25 nor after 65 years. In the series of 30 subjects, the proportion of red marrow surface area and bulk T1 values of femoral red marrow were significantly negatively correlated with hemoglobin blood levels but not with blood cell counts.
CONCLUSION: The MR appearance of proximal femur red marrow is influenced by age and sex. A relationship with hemoglobin blood level is demonstrated.

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Year:  1997        PMID: 9361354     DOI: 10.1007/s002560050291

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


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