Literature DB >> 9360603

C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site.

J Brandsen, S Werten, P C van der Vliet, M Meisterernst, J Kroon, P Gros.   

Abstract

The crystal structure of human replication and transcription cofactor PC4CTD reveals a dimer with two single-stranded (ss)DNA binding channels running in opposite directions to each other. This arrangement suggests a role in establishment or maintenance of melted DNA at promoters or origins of replication.

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Year:  1997        PMID： 9360603     DOI： 10.1038/nsb1197-900

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN： 1072-8368


  31 in total

1.  Purification of transcription cofactor complex CRSP.

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2.  Structure of an RNA polymerase II preinitiation complex.

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Journal:  Proc Natl Acad Sci U S A       Date:  2015-10-19       Impact factor: 11.205

3.  DNA binding properties of the adenovirus DNA replication priming protein pTP.

Authors:  R N de Jong; L A T Meijer; P C van der Vliet
Journal:  Nucleic Acids Res       Date:  2003-06-15       Impact factor: 16.971

4.  X-ray structure of Pur-alpha reveals a Whirly-like fold and an unusual nucleic-acid binding surface.

Authors:  Almut Graebsch; Stéphane Roche; Dierk Niessing
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-21       Impact factor: 11.205

5.  Interaction of PC4 with melted DNA inhibits transcription.

Authors:  S Werten; G Stelzer; A Goppelt; F M Langen; P Gros; H T Timmers; P C Van der Vliet; M Meisterernst
Journal:  EMBO J       Date:  1998-09-01       Impact factor: 11.598

6.  A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4.

Authors:  Wezley C Griffin; Jun Gao; Alicia K Byrd; Shubeena Chib; Kevin D Raney
Journal:  J Biol Chem       Date:  2017-04-17       Impact factor: 5.157

7.  Interaction of positive coactivator 4 with histone 3.3 protein is essential for transcriptional activation of the luteinizing hormone receptor gene.

Authors:  Peng Zhao; Raghuveer Kavarthapu; Rajakumar Anbazhagan; Mingjuan Liao; Maria L Dufau
Journal:  Biochim Biophys Acta Gene Regul Mech       Date:  2018-09-13       Impact factor: 4.490

Review 8.  Sub1/PC4, a multifaceted factor: from transcription to genome stability.

Authors:  Miguel Garavís; Olga Calvo
Journal:  Curr Genet       Date:  2017-05-31       Impact factor: 3.886

9.  Manual classification strategies in the ECOD database.

Authors:  Hua Cheng; Yuxing Liao; R Dustin Schaeffer; Nick V Grishin
Journal:  Proteins       Date:  2015-05-08

10.  The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage.

Authors:  Jen-Yeu Wang; Altaf Hossain Sarker; Priscilla K Cooper; Michael R Volkert
Journal:  Mol Cell Biol       Date:  2004-07       Impact factor: 4.272
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