| Literature DB >> 9360599 |
P L Clark, Z P Liu, J Rizo, L M Gierasch.
Abstract
The time course of folding of a small beta-sheet protein reveals formation of a central ligand binding cavity before the consolidation of the native hydrogen bonding network. These results suggest that side chain interactions and not stable hydrogen bonding determine the beta-sheet architecture and play crucial roles in the overall chain topology.Entities:
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Year: 1997 PMID： 9360599 DOI： 10.1038/nsb1197-883
Source DB: PubMed Journal: Nat Struct Biol ISSN： 1072-8368