| Literature DB >> 9358200 |
O Schück1, M Bohdanecká, J Sedivý, M Krajícková, M Chadimová, K Matousovic.
Abstract
Experimental chronic renal insufficiency (produced by 5/6 ablation of renal parenchyma) is associated with changes in the kinetics of oral (intragastric) cyclosporine A (CyA). Compared with animals with intact renal parenchyma, significantly lower levels of CyA are reached under these conditions. The factors responsible for reduced CyA availability under these conditions have not yet been identified.Entities:
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Year: 1997 PMID： 9358200 DOI： 10.1007/BF03189808
Source DB: PubMed Journal: Eur J Drug Metab Pharmacokinet ISSN： 0378-7966 Impact factor: 2.441