| Literature DB >> 9357315 |
W F Mangel1, D L Toledo, J Ding, R M Sweet, W J McGrath.
Abstract
The adenovirus proteinase (AVP) uses both an 11-amino acid peptide (pVIc) and the viral DNA as cofactors to increase its catalytic rate constant 6000-fold. The crystal structure of an AVP-pVIc complex at 2.6-A resolution reveals a new protein fold of an enzyme that is the first member of a new class of cysteine proteinases, which arose via convergent evolution.Entities:
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Year: 1997 PMID： 9357315 DOI： 10.1016/s0968-0004(97)01123-7
Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807