OBJECTIVE: The purpose of this study was to determine whether adolescent schizophrenia is characterized by neuropsychological deficits. METHOD: The performance on a battery of neuropsychological tests of 17 adolescents with schizophrenia (mean age = 15.71 years) was compared with that of 17 normal adolescents (mean age = 15.12 years). RESULTS: Compared with the normal subjects, the patients were impaired on 10 of the 13 measures; larger effect sizes were shown for measures involving working memory and attention than for those involving secondary memory, generative naming, and executive functions. CONCLUSIONS: Adolescents with schizophrenia have generalized cognitive dysfunction, which is most apparent on tests of attention and working memory.
OBJECTIVE: The purpose of this study was to determine whether adolescent schizophrenia is characterized by neuropsychological deficits. METHOD: The performance on a battery of neuropsychological tests of 17 adolescents with schizophrenia (mean age = 15.71 years) was compared with that of 17 normal adolescents (mean age = 15.12 years). RESULTS: Compared with the normal subjects, the patients were impaired on 10 of the 13 measures; larger effect sizes were shown for measures involving working memory and attention than for those involving secondary memory, generative naming, and executive functions. CONCLUSIONS: Adolescents with schizophrenia have generalized cognitive dysfunction, which is most apparent on tests of attention and working memory.
Authors: Jens Richardt M Jepsen; Birgitte Fagerlund; Anne Katrine Pagsberg; Anne Marie R Christensen; Merete Nordentoft; Erik L Mortensen Journal: Eur Child Adolesc Psychiatry Date: 2010-08-01 Impact factor: 4.785
Authors: S R Sponheim; R E Jung; L J Seidman; R I Mesholam-Gately; D S Manoach; D S O'Leary; B C Ho; N C Andreasen; J Lauriello; S C Schulz Journal: J Psychiatr Res Date: 2009-10-29 Impact factor: 4.791
Authors: Arantzazu Zabala; Marta Rapado; Celso Arango; Olalla Robles; Elena de la Serna; Cristina González; José Manuel Rodríguez-Sánchez; Patricia Andrés; María Mayoral; Igor Bombín Journal: Eur Arch Psychiatry Clin Neurosci Date: 2009-09-19 Impact factor: 5.270
Authors: Jens Richardt Moellegaard Jepsen; Birgitte Fagerlund; Anne Katrine Pagsberg; Anne Marie R Christensen; Rikke W Hilker; Merete Nordentoft; Erik L Mortensen Journal: Eur Child Adolesc Psychiatry Date: 2009-09-10 Impact factor: 4.785