Literature DB >> 935656

Specificity of the digoxin radioimmunoassay with respect to dihydrodigoxin.

W G Kramer, M S Bathala, R H Reuning.   

Abstract

An investigation was conducted to determine the specificity of the digoxin antibody provided in a commercially available radioimmunoassay kit with respect to dihydrodigoxin. Over the concentration range of 0.5 to 8.0 ng./ml. dihydrodigoxin displaced the 125I digoxin derivative from the antibody to a degree that could be significant at clinically observed serum and urine digoxin concentrations.

Entities:  

Mesh:

Substances:

Year:  1976        PMID: 935656

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  2 in total

1.  Pharmacokinetics of digoxin: relationship between response intensity and predicted compartmental drug levels in man.

Authors:  W G Kramer; A J Kolibash; R P Lewis; M S Bathala; J A Visconti; R H Reuning
Journal:  J Pharmacokinet Biopharm       Date:  1979-02

2.  Comparison of the pharmacokinetics of digoxin and dihydrodigoxin in cats in single-dose studies.

Authors:  N Heinz; H Flasch
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-06       Impact factor: 3.000

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.