| Literature DB >> 9355958 |
E Jouanguy1, F Altare, S Lamhamedi-Cherradi, J L Casanova.
Abstract
Human interferon-gamma receptor 1 (IFNGR-1) deficiency is a newly identified autosomal recessive inherited immune disorder. Children with IFNGR-1 deficiency exhibit a severe, profound and selective susceptibility to weakly virulent mycobacteria, such as bacillus Calmette-Guerin (BCG) vaccine or environmental nontuberculous mycobacteria (NTM). This review compares the infections found in IFNGR-1-deficient children to those in IFN-gamma-deficient or IFNGR-1-deficient mice.Entities:
Mesh:
Substances:
Year: 1997 PMID: 9355958 DOI: 10.1089/jir.1997.17.583
Source DB: PubMed Journal: J Interferon Cytokine Res ISSN: 1079-9907 Impact factor: 2.607