Literature DB >> 9353234

Plasmid DNA expression systems for the purpose of immunization.

H L Davis1.   

Abstract

DNA vaccines induce immune responses against antigens synthesized in vivo after direct introduction of the DNA's encoding sequences. This unique approach to immunization may overcome deficits of traditional antigen-based approaches and provide safe and effective prophylactic and therapeutic vaccines. DNA vaccines are also useful as a research tool, such as for production of monoclonal antibodies. Efforts are now focusing on understanding the mechanism of antigen presentation and the adjuvant effect of immunostimulatory CpG motifs in the vectors to aid optimization of DNA vaccines.

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Year:  1997        PMID： 9353234     DOI： 10.1016/s0958-1669(97)80041-9

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  11 in total

1.  Synergistic effect of formulated plasmid and needle-free injection for genetic vaccines.

Authors:  K Anwer; K A Earle; M Shi; J Wang; R J Mumper; B Proctor; K Jansa; H C Ledebur; S Davis; W Eaglstein; A P Rolland
Journal:  Pharm Res       Date:  1999-06       Impact factor: 4.200

2.  Granulocyte-macrophage colony-stimulating factor priming plus papillomavirus E6 DNA vaccination: effects on papilloma formation and regression in the cottontail rabbit papillomavirus--rabbit model.

Authors:  S A Leachman; R E Tigelaar; M Shlyankevich; M D Slade; M Irwin; E Chang; T C Wu; W Xiao; S Pazhani; D Zelterman; J L Brandsma
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

3.  Immunogenicity of a bovine herpesvirus 1 glycoprotein D DNA vaccine complexed with bovine neutrophil beta-defensin 3.

Authors:  Sarah Mackenzie-Dyck; Laura Latimer; Ethel Atanley; Jennifer Kovacs-Nolan; Sam Attah-Poku; Lorne A Babiuk; Sylvia van Drunen Littel-van den Hurk
Journal:  Clin Vaccine Immunol       Date:  2014-11-05

4.  DNA immunization to prevent autoimmune diabetes.

Authors:  B Coon; L L An; J L Whitton; M G von Herrath
Journal:  J Clin Invest       Date:  1999-07       Impact factor: 14.808

5.  Codon optimization of the tat antigen of human immunodeficiency virus type 1 generates strong immune responses in mice following genetic immunization.

Authors:  Lakshmi Ramakrishna; Krishnamurthy Kumar Anand; Kumarasamypet M Mohankumar; Udaykumar Ranga
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

6.  Adjuvant effects of L. acidophilus LW1 on immune responses to the foot-and-mouth disease virus DNA vaccine in mice.

Authors:  Junhong Su; Jidong Li; Haixue Zheng; Yanan You; Xuenong Luo; Yungang Li; Xueqiang Li; Xusheng Ma; Junjun Li; Yongxi Dou; Xuepeng Cai
Journal:  PLoS One       Date:  2014-08-13       Impact factor: 3.240

7.  DNA immunization as an efficient strategy for vaccination.

Authors:  Azam Bolhassani; Sima Rafati Yazdi
Journal:  Avicenna J Med Biotechnol       Date:  2009-07

8.  DNA vaccines: improving expression of antigens.

Authors:  Helen S Garmory; Katherine A Brown; Richard W Titball
Journal:  Genet Vaccines Ther       Date:  2003-09-16

Review 9.  The role of high-resolution imaging in the evaluation of nanosystems for bioactive encapsulation and targeted nanotherapy.

Authors:  Kianoush Khosravi-Darani; Abbas Pardakhty; Hamid Honarpisheh; V S N Malleswara Rao; M Reza Mozafari
Journal:  Micron       Date:  2007-07-03       Impact factor: 2.251

10.  Gene gun-supported DNA immunisation of chicken for straightforward production of poxvirus-specific IgY antibodies.

Authors:  Peter T Witkowski; Daniel R Bourquain; Oliver Hohn; Rüdiger Schade; Andreas Nitsche
Journal:  J Immunol Methods       Date:  2008-12-17       Impact factor: 2.303
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