| Literature DB >> 9353225 |
Abstract
The components responsible for protein translocation across the endoplasmic reticulum membrane have been identified and their functions have been clarified in vitro. The structural features of the signal peptide specify the factors and pathways of membrane translocation. Various chaperones and folding enzymes are involved in the folding and quality control of secretory proteins in the lumen.Mesh:
Substances:
Year: 1997 PMID: 9353225 DOI: 10.1016/s0958-1669(97)80035-3
Source DB: PubMed Journal: Curr Opin Biotechnol ISSN: 0958-1669 Impact factor: 9.740