Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Effects of the CYP2D6 genotype on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese schizophrenic patients.

Literature DB >> 9352580

Effects of the CYP2D6 genotype on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese schizophrenic patients.

A Suzuki¹, K Otani, K Mihara, N Yasui, S Kaneko, Y Inoue, K Hayashi.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1997 PMID： 9352580 DOI： 10.1097/00008571-199710000-00013

Source DB: PubMed Journal: Pharmacogenetics ISSN： 0960-314X

Keyword Cloud
Cited

× No keyword cloud information.

10 in total

1. Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation.

Authors: K J Aitchison; J Munro; P Wright; S Smith; A J Makoff; C Sachse; P C Sham; R M Murray; D A Collier; R W Kerwin
Journal: Br J Clin Pharmacol Date: 1999-09 Impact factor: 4.335

Review 2. Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs.

Authors: Leif Bertilsson; Marja-Liisa Dahl; Per Dalén; Ayman Al-Shurbaji
Journal: Br J Clin Pharmacol Date: 2002-02 Impact factor: 4.335

3. Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients.

Authors: H K Roh; J Y Chung; D Y Oh; C S Park; J O Svensson; M L Dahl; L Bertilsson
Journal: Br J Clin Pharmacol Date: 2001-09 Impact factor: 4.335

Review 4. Pharmacokinetics of haloperidol: an update.

Authors: S Kudo; T Ishizaki
Journal: Clin Pharmacokinet Date: 1999-12 Impact factor: 6.447

5. Association study between functional polymorphisms in the cytochrome P450 1A2 and 2D6 genes and polydipsia in schizophrenia.

Authors: Chima Matsumoto; Takahiro Shinkai; Vincenzo De Luca; Hiroko Hori; Rudi Hwang; Osamu Ohmori; James L Kennedy; Jun Nakamura
Journal: Neuromolecular Med Date: 2006 Impact factor: 3.843

Effects of the CYP2D6 genotype on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese schizophrenic patients.

1. Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation.

Review 2. Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs.

3. Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients.

Review 4. Pharmacokinetics of haloperidol: an update.

5. Association study between functional polymorphisms in the cytochrome P450 1A2 and 2D6 genes and polydipsia in schizophrenia.

6. Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia.

7. Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.

8. Haloperidol plasma concentration in Japanese psychiatric subjects with gene duplication of CYP2D6.

Review 9. Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: useful aid to prescribing?

Review 10. Clinical applications of CYP genotyping in psychiatry.