Literature DB >> 9352540

Fluorine-18-labeled fluorine gas for synthesis of tracer molecules.

J Bergman1, O Solin.   

Abstract

The aim of this work was to develop a method to produce 18F-labeled fluorine gas ([18F]F2) with high specific radioactivity (SA, radioactivity/mass-ratio). 18F-Labeled methyl fluoride ([18F]CH3F) was synthesized from [18F]F-aq and mixed with carrier F2 in an inert neon matrix. The constituents were atomized in an electric discharge, after which a rearrangement and 18F for 19F exchange took place. [18F]F2 with a specific radioactivity of up to 55 GBq/mumol is available for the labeling synthesis of tracers for positron emission tomography (PET).

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Year:  1997        PMID： 9352540     DOI： 10.1016/s0969-8051(97)00078-4

Source DB:  PubMed          Journal:  Nucl Med Biol        ISSN： 0969-8051            Impact factor:   2.408


  34 in total

1.  Usefulness of a dopamine transporter PET ligand [(18)F]beta-CFT in assessing disability in Parkinson's disease.

Authors:  J O Rinne; H Ruottinen; J Bergman; M Haaparanta; P Sonninen; O Solin
Journal:  J Neurol Neurosurg Psychiatry       Date:  1999-12       Impact factor: 10.154

2.  Personality traits and brain dopaminergic function in Parkinson's disease.

Authors:  V Kaasinen; E Nurmi; J Bergman; O Eskola; O Solin; P Sonninen; J O Rinne
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-30       Impact factor: 11.205

3.  Radiochemistry: Flipping fluoride's reactivity.

Authors:  Véronique Gouverneur
Journal:  Nat Chem       Date:  2012-02-21       Impact factor: 24.427

4.  Uptake of 4-borono-2-[18F]fluoro-L-phenylalanine in sporadic and neurofibromatosis 2-related schwannoma and meningioma studied with PET.

Authors:  Katja Havu-Aurén; Johanna Kiiski; Kaisa Lehtiö; Olli Eskola; Martti Kulvik; Ville Vuorinen; Vesa Oikonen; Jyrki Vähätalo; Juha Jääskeläinen; Heikki Minn
Journal:  Eur J Nucl Med Mol Imaging       Date:  2006-07-29       Impact factor: 9.236

5.  Fluorine-18: an untapped resource in inorganic chemistry.

Authors:  Cassis Varlow; Daniel Szames; Kenneth Dahl; Vadim Bernard-Gauthier; Neil Vasdev
Journal:  Chem Commun (Camb)       Date:  2018-10-18       Impact factor: 6.222

6.  Radiosynthesis and Preclinical Evaluation of an α2A-Adrenoceptor Tracer Candidate, 6-[18F]Fluoro-marsanidine.

Authors:  Anna Krzyczmonik; Thomas Keller; Francisco R López-Picón; Sarita Forsback; Anna K Kirjavainen; Jatta S Takkinen; Aleksandra Wasilewska; Mika Scheinin; Merja Haaparanta-Solin; Franciszek Sączewski; Olof Solin
Journal:  Mol Imaging Biol       Date:  2019-10       Impact factor: 3.488

Review 7.  Development of (18)F-labeled radiotracers for neuroreceptor imaging with positron emission tomography.

Authors:  Peter Brust; Jörg van den Hoff; Jörg Steinbach
Journal:  Neurosci Bull       Date:  2014-08-29       Impact factor: 5.203

8.  Tracer level electrophilic synthesis and pharmacokinetics of the hypoxia tracer [(18)F]EF5.

Authors:  Olli Eskola; Tove J Grönroos; Sarita Forsback; Johanna Tuomela; Gaber Komar; Jörgen Bergman; Pirkko Härkönen; Merja Haaparanta; Heikki Minn; Olof Solin
Journal:  Mol Imaging Biol       Date:  2012-04       Impact factor: 3.488

9.  Copper-Mediated Aminoquinoline-Directed Radiofluorination of Aromatic C-H Bonds with K18 F.

Authors:  So Jeong Lee; Katarina J Makaravage; Allen F Brooks; Peter J H Scott; Melanie S Sanford
Journal:  Angew Chem Int Ed Engl       Date:  2019-01-18       Impact factor: 15.336

10.  Fast growth associated with aberrant vasculature and hypoxia in fibroblast growth factor 8b (FGF8b) over-expressing PC-3 prostate tumour xenografts.

Authors:  Johanna Tuomela; Tove J Grönroos; Maija P Valta; Jouko Sandholm; Aleksi Schrey; Jani Seppänen; Päivi Marjamäki; Sarita Forsback; Ilpo Kinnunen; Olof Solin; Heikki Minn; Pirkko L Härkönen
Journal:  BMC Cancer       Date:  2010-10-30       Impact factor: 4.430
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