| Literature DB >> 9352073 |
K Ito1, S Ikeda, T Shibata, T Yano, S Horikawa.
Abstract
Total hepatic ischemia was induced by clamping the hepatic artery, portal vein, and bile duct. After 15 min hepatic ischemia, we examined a time course of the changes in the steady-state levels of heme oxygenase-1 (HO-1) mRNA and protein in the livers. The levels of HO-1 mRNA was transiently induced and peaked at 4 h after the start of reperfusion. In addition, a pattern of the time course of HO-1 protein levels was similar to that of HO-1 mRNA levels. Immunohistochemical analysis clearly showed that the localization of HO-1 protein induced by hepatic ischemia was restricted to the hepatocytes in the pericentral vein.Entities:
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Year: 1997 PMID： 9352073 DOI： 10.1080/15216549700204351
Source DB: PubMed Journal: Biochem Mol Biol Int ISSN： 1039-9712