Literature DB >> 9351483

Drug use by demented and non-demented elderly people.

P Wills1, C B Claesson, L Fratiglioni, J Fastbom, M Thorslund, B Winblad.   

Abstract

AIM: to determine the use of drugs by demented and non-demented elderly people in a population, by dementia status and type, age, sex and accommodation type.
METHOD: data were obtained from the Kungsholmen project, a longitudinal community study of people over 75 in Stockholm, Sweden.
RESULTS: 85% used at least one medicinal drug, and of these 12% were demented. Mean numbers of drugs used were 2.8 for demented and 3.2 for non-demented people. 45% of demented people and 38% of non-demented people used psychotropic agents. Psychotropic use was higher in women and increased with institutionalization. Antipsychotic agents were used more by demented (22%) than by non-demented (3.5%) people: this was largely explained by differences in accommodation type. The odds ratio (OR) for use of antipsychotics by those in institutions compared with those living in their own homes was 9.32. Opioids were commonly prescribed for demented people. The proportions taking opioids in those using analgesics were 42% in demented and 23% in non-demented people (OR 2.07). Laxatives were used by 18% of the demented people in institutions compared with 39% of non-demented people in institutions.
CONCLUSION: being in an institution had a stronger association with the use of certain drugs (e.g. psychotropics) than did dementia status. Demented people, especially those in institutions, used a large number of antipsychotics and opioids, but fewer laxatives and minor analgesics. Prescribers and institutional staff should be aware of these factors so they can optimize patient treatment.

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Year:  1997        PMID: 9351483     DOI: 10.1093/ageing/26.5.383

Source DB:  PubMed          Journal:  Age Ageing        ISSN: 0002-0729            Impact factor:   10.668


  15 in total

1.  Pain treatment in elderly persons with and without dementia: a population-based study of institutionalized and home-dwelling elderly.

Authors:  Ylva Haasum; Johan Fastbom; Laura Fratiglioni; Ingemar Kåreholt; Kristina Johnell
Journal:  Drugs Aging       Date:  2011-04-01       Impact factor: 3.923

2.  Undertreatment of osteoporosis in persons with dementia? A population-based study.

Authors:  Y Haasum; J Fastbom; L Fratiglioni; K Johnell
Journal:  Osteoporos Int       Date:  2011-04-16       Impact factor: 4.507

3.  The use of angiotensin-converting enzyme inhibitors and other drugs with cardiovascular effects by non-demented and demented elderly with a clinical diagnosis of heart failure. A population-based study of the very old.

Authors:  Inga Klarin; Johan Fastbom; Anders Wimo
Journal:  Eur J Clin Pharmacol       Date:  2006-05-10       Impact factor: 2.953

4.  Gender disparities in the pharmacological treatment of cardiovascular disease and diabetes mellitus in the very old: an epidemiological, cross-sectional survey.

Authors:  Jon Brännström; Katarina Hamberg; Lena Molander; Hugo Lövheim; Yngve Gustafson
Journal:  Drugs Aging       Date:  2011-12-01       Impact factor: 3.923

5.  Reducing Psychotropic Use in Older Non-demented Spanish Care Home Residents: a Before-After Comparison of Three Methods.

Authors:  Curtis L Petersen; David Curto; Manish K Mishra; Pedro Cano; William B Weeks
Journal:  J Gen Intern Med       Date:  2019-11-11       Impact factor: 5.128

6.  Drug use by the elderly in general practice: effects on upper gastrointestinal symptoms.

Authors:  Alberto Pilotto; Marilisa Franceschi; Dino Vitale; Augusto Zaninelli; Giulio Masotti; Franco Rengo
Journal:  Eur J Clin Pharmacol       Date:  2005-12-30       Impact factor: 2.953

7.  NSAID and aspirin use by the elderly in general practice: effect on gastrointestinal symptoms and therapies.

Authors:  Alberto Pilotto; Marilisa Franceschi; Gioacchino Leandro; Francesco Di Mario
Journal:  Drugs Aging       Date:  2003       Impact factor: 3.923

8.  Nursing-home residents and their drug use: a comparison between mentally intact and mentally impaired residents. The Bergen district nursing home (BEDNURS) study.

Authors:  Harald A Nygaard; Mala Naik; Sabine Ruths; Jørund Straand
Journal:  Eur J Clin Pharmacol       Date:  2003-08-12       Impact factor: 2.953

9.  Drug use and low blood pressure in the elderly: a study of data from the kungsholmen project.

Authors:  G Passare; Z Guo; B Winblad; J Fastbom
Journal:  Clin Drug Investig       Date:  1998       Impact factor: 2.859

Review 10.  Drug use in patients with dementia: a register-based study in the health region of Girona (Catalonia/Spain).

Authors:  Pilar Avila-Castells; Josep Garre-Olmo; Laia Calvó-Perxas; Oriol Turró-Garriga; Elisabet Alsina; Olga Carmona; Héctor Perkal; Anna Maria Roig; Josep Ma Cuy; Manuela Lozano; Albert Molins; Natàlia Vallmajó; Secundino López-Pousa
Journal:  Eur J Clin Pharmacol       Date:  2012-11-23       Impact factor: 2.953

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