Literature DB >> 9351343

Sunlight and the onset of skin cancer.

D E Brash1.   

Abstract

The photons of sunlight precipitate a series of genetic events in skin leading to cancer. These events involve somatic mutations as well as inherited alleles. Competition between cell populations ensues, as a single mutated cell expands into a clone. Thus cancer involves both a single-cell problem and a many-cell problem; in skin cancer, sunlight appears to drive both.

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Year:  1997        PMID: 9351343     DOI: 10.1016/s0168-9525(97)01246-8

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  67 in total

Review 1.  Biomarkers as surrogates for cancer development.

Authors:  E Hawk; J L Viner; J A Lawrence
Journal:  Curr Oncol Rep       Date:  2000-05       Impact factor: 5.075

2.  Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites.

Authors:  L Haracska; I Unk; R E Johnson; E Johansson; P M Burgers; S Prakash; L Prakash
Journal:  Genes Dev       Date:  2001-04-15       Impact factor: 11.361

3.  Role of DNA polymerase eta in the bypass of a (6-4) TT photoproduct.

Authors:  R E Johnson; L Haracska; S Prakash; L Prakash
Journal:  Mol Cell Biol       Date:  2001-05       Impact factor: 4.272

4.  Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis.

Authors:  J G Einspahr; D S Alberts; J A Warneke; P Bozzo; J Basye; T M Grogan; M A Nelson; G T Bowden
Journal:  Neoplasia       Date:  1999-11       Impact factor: 5.715

5.  Role for p53 in the recovery of transcription and protection against apoptosis induced by ultraviolet light.

Authors:  B C McKay; M Ljungman
Journal:  Neoplasia       Date:  1999-08       Impact factor: 5.715

6.  Direct observation of thymine dimer repair in DNA by photolyase.

Authors:  Ya-Ting Kao; Chaitanya Saxena; Lijuan Wang; Aziz Sancar; Dongping Zhong
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-16       Impact factor: 11.205

7.  C/EBPalpha is a DNA damage-inducible p53-regulated mediator of the G1 checkpoint in keratinocytes.

Authors:  Kyungsil Yoon; Robert C Smart
Journal:  Mol Cell Biol       Date:  2004-12       Impact factor: 4.272

8.  C/EBPα regulates CRL4(Cdt2)-mediated degradation of p21 in response to UVB-induced DNA damage to control the G1/S checkpoint.

Authors:  Jonathan R Hall; Michael S Bereman; Angelito I Nepomuceno; Elizabeth A Thompson; David C Muddiman; Robert C Smart
Journal:  Cell Cycle       Date:  2014       Impact factor: 4.534

9.  A functional SNP in the MDM2 promoter, pigmentary phenotypes, and risk of skin cancer.

Authors:  Hongmei Nan; Abrar A Qureshi; David J Hunter; Jiali Han
Journal:  Cancer Causes Control       Date:  2008-09-24       Impact factor: 2.506

10.  A prospective study of telomere length and the risk of skin cancer.

Authors:  Jiali Han; Abrar A Qureshi; Jennifer Prescott; Qun Guo; Li Ye; David J Hunter; Immaculata De Vivo
Journal:  J Invest Dermatol       Date:  2008-07-31       Impact factor: 8.551

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