| Literature DB >> 935125 |
D J Byrd, H W Berthold, K F Trefz, W Kochen, G Gilli, K Schärer, H W Schüler, H W Asbach.
Abstract
Tryptophan and some indolic metabolites were studied in urine, plasma and dialysate of uraemic patients using thin-layer- and high-pressure liquid chromatography. Some new metabolites: indole-3-carboxylic acid, indole-3-carbaldehyde, indolelactic acid and N-acetyltryptophan were detected. Levels of the latter two metabolites in urine, dialysate and especially plasma suggest increased transamination of tryptophan and a possible defect in renal amino acid acylase in uraemia.Entities:
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Year: 1976 PMID： 935125
Source DB: PubMed Journal: Proc Eur Dial Transplant Assoc ISSN： 0071-2736