Literature DB >> 9351176

Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 gene.

S H Speck1, T Chatila, E Flemington.   

Abstract

The switch from latent infection to virus replication in Epstein-Barr virus (EBV)-infected B cells is initiated by expression of the viral BZLF1 gene. Recent studies have identified the key cellular transcription factors involved in regulating this switch in viral programs and the signal transduction pathways to which they respond. Understanding this switch may facilitate development of strategies to interfere with EBV infection.

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Year:  1997        PMID： 9351176     DOI： 10.1016/S0966-842X(97)01129-3

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  119 in total

1.  Genetic dissection of cell growth arrest functions mediated by the Epstein-Barr virus lytic gene product, Zta.

Authors:  A Rodriguez; M Armstrong; D Dwyer; E Flemington
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

2.  The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators.

Authors:  R Feederle; M Kost; M Baumann; A Janz; E Drouet; W Hammerschmidt; H J Delecluse
Journal:  EMBO J       Date:  2000-06-15       Impact factor: 11.598

3.  Upregulation of tyrosine kinase TKT by the Epstein-Barr virus transactivator Zta.

Authors:  J Lu; S Y Chen; H H Chua; Y S Liu; Y T Huang; Y Chang; J Y Chen; T S Sheen; C H Tsai
Journal:  J Virol       Date:  2000-08       Impact factor: 5.103

4.  Nucleoprotein structure of immediate-early promoters Zp and Rp and of oriLyt of latent Epstein-Barr virus genomes.

Authors:  Hans Helmut Niller; Daniel Salamon; Jörg Uhlig; Stefanie Ranf; Marcus Granz; Fritz Schwarzmann; Hans Wolf; Janos Minarovits
Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

5.  Autostimulation of the Epstein-Barr virus BRLF1 promoter is mediated through consensus Sp1 and Sp3 binding sites.

Authors:  T Ragoczy; G Miller
Journal:  J Virol       Date:  2001-06       Impact factor: 5.103

6.  The CBP bromodomain and nucleosome targeting are required for Zta-directed nucleosome acetylation and transcription activation.

Authors:  Zhong Deng; Chi-Ju Chen; Michaela Chamberlin; Fang Lu; Gerd A Blobel; David Speicher; Lisa Ann Cirillo; Kenneth S Zaret; Paul M Lieberman
Journal:  Mol Cell Biol       Date:  2003-04       Impact factor: 4.272

7.  Disruption of gammaherpesvirus 68 gene 50 demonstrates that Rta is essential for virus replication.

Authors:  Iglika V Pavlova; Herbert W Virgin; Samuel H Speck
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103

8.  Lytic but not latent replication of epstein-barr virus is associated with PML and induces sequential release of nuclear domain 10 proteins.

Authors:  P Bell; P M Lieberman; G G Maul
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

9.  Signal Transduction and Transcription Factor Modification during Reactivation of Epstein-Barr Virus from Latency.

Authors:  Helen Bryant; Paul J Farrell
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

10.  Epstein-Barr virus utilizes Ikaros in regulating its latent-lytic switch in B cells.

Authors:  Tawin Iempridee; Jessica A Reusch; Andrew Riching; Eric C Johannsen; Sinisa Dovat; Shannon C Kenney; Janet E Mertz
Journal:  J Virol       Date:  2014-02-12       Impact factor: 5.103
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