Literature DB >> 9350345

Mapping the common antigenic determinants in avidin and streptavidin.

N Subramanian1, P R Adiga.   

Abstract

An epitope scan analysis of the whole sequence of avidin and core streptavidin using polyclonal antibodies to these two antigens reveal the presence of multiple common epitopes in both the proteins. These antigenic determinants consist mostly of either identical or similar residues. The antibody recognition sites in both antigens are shown to be localized to homologous regions.

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Year:  1997        PMID： 9350345     DOI： 10.1080/15216549700204161

Source DB:  PubMed          Journal:  Biochem Mol Biol Int        ISSN： 1039-9712


  6 in total

1.  Mutations for decreasing the immunogenicity and maintaining the function of core streptavidin.

Authors:  Kyohei Yumura; Mihoko Ui; Hirofumi Doi; Takao Hamakubo; Tatsuhiko Kodama; Kouhei Tsumoto; Akira Sugiyama
Journal:  Protein Sci       Date:  2013-01-04       Impact factor: 6.725

2.  Reduced antibody response to streptavidin through site-directed mutagenesis.

Authors:  D L Meyer; J Schultz; Y Lin; A Henry; J Sanderson; J M Jackson; S Goshorn; A R Rees; S S Graves
Journal:  Protein Sci       Date:  2001-03       Impact factor: 6.725

3.  Characterization of poultry egg-white avidins and their potential as a tool in pretargeting cancer treatment.

Authors:  Vesa P Hytönen; Olli H Laitinen; Alessandro Grapputo; Anu Kettunen; Janne Savolainen; Nisse Kalkkinen; Ari T Marttila; Henri R Nordlund; Thomas K M Nyholm; Giovanni Paganelli; Markku S Kulomaa
Journal:  Biochem J       Date:  2003-05-15       Impact factor: 3.857

4.  Prescreening of Nicotine Hapten Linkers in Vitro To Select Hapten-Conjugate Vaccine Candidates for Pharmacokinetic Evaluation in Vivo.

Authors:  Viswanath Arutla; Joseph Leal; Xiaowei Liu; Sriram Sokalingam; Michael Raleigh; Adejimi Adaralegbe; Li Liu; Paul R Pentel; Sidney M Hecht; Yung Chang
Journal:  ACS Comb Sci       Date:  2017-04-17       Impact factor: 3.784

5.  Biochemical and biological characterization of a new oxidized avidin with enhanced tissue binding properties.

Authors:  Antonio Verdoliva; Piero Bellofiore; Vincenzo Rivieccio; Sergio Catello; Maurizio Colombo; Claudio Albertoni; Antonio Rosi; Barbara Leoni; Anna Maria Anastasi; Rita De Santis
Journal:  J Biol Chem       Date:  2010-01-25       Impact factor: 5.157

Review 6.  Cupid and Psyche system for the diagnosis and treatment of advanced cancer.

Authors:  Akira Sugiyama; Takeshi Kawamura; Toshiya Tanaka; Hirofumi Doi; Takefumi Yamashita; Keiko Shinoda; Hideaki Fujitani; Kenzo Yamatsugu; Yohei Shimizu; Toshifumi Tatsumi; Kazuki Takahashi; Motomu Kanai; Eiichi Mizohata; Tatsuya Kawato; Takefumi Doi; Tsuyoshi Inoue; Tatsuhiko Kodama
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2019       Impact factor: 3.493
  6 in total

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