Literature DB >> 93500

5-Hydroxytryptamine and myoclonus induced by 1,2-di-hydroxybenzene (catechol) in the guinea-pig.

D Chadwick, P Jenner, C D Marsden.   

Abstract

Myoclonus induced by catechol in the guinea-pig is not altered by manipulation of cerebral 5-hydroxytryptamine (5-HT). The administration of catechol does not alter brain levels of 5-HT or its metabolite 5-hydroxyindole acetic acid. This form of myoclonus therefore is not of relevance to the 5-HT-sensitive post-anoxic action myoclonus occurring in man.

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Year:  1979        PMID： 93500      PMCID： PMC2043656          DOI： 10.1111/j.1476-5381.1979.tb10837.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  12 in total

1.  Proceedings: Effects of cholinergic drugs on catechol evoked convulsions.

Authors:  A Angel; D G Dewhurst
Journal:  J Physiol       Date:  1976-01       Impact factor: 5.182

2.  The convulsive action of 1,2-dihydroxybenzene in the anaesthetized rat.

Authors:  A Angel; R N Lemon
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1973-04

3.  An analysis of the myoclonic jerks produced by 1, 2-dihydroxybenzene in the rat.

Authors:  A Angel; R N Lemon
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1973-12

4.  An analysis of the effect of 1,2-dihydroxybenzene on transmission through the dorsal column sensory pathway.

Authors:  A Angel
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1969-10

5.  5-hydroxytryptophan-induced myoclonus in guinea pigs. A physiological and pharmacological investigations.

Authors:  D Chadwick; M Hallett; P Jenner; C D Marsden
Journal:  J Neurol Sci       Date:  1978-01       Impact factor: 3.181

6.  Sensorimotor cortical representation in the rat and the role of the cortex in the production of sensory myoclonic jerks.

Authors:  A Angel; R N Lemon
Journal:  J Physiol       Date:  1975-06       Impact factor: 5.182

7.  p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus.

Authors:  E C Hwang; M H Van Woert
Journal:  Neurology       Date:  1978-10       Impact factor: 9.910

8.  Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.

Authors:  D Chadwick; M Hallett; R Harris; P Jenner; E H Reynolds; C D Marsden
Journal:  Brain       Date:  1977-09       Impact factor: 13.501

9.  A pharmacological study of the spontaneous convulsive activity induced by 1,2-dihydroxybenzene (catechol) in the anaesthetized mouse.

Authors:  A Angel; K A Clarke; D G Dewhurst
Journal:  Br J Pharmacol       Date:  1977-11       Impact factor: 8.739

10.  5-Hydroxytryptophan-induced myoclonus in guinea pigs and the possible role of serotonin in infantile myoclonus.

Authors:  H L Klawans; C Goetz; W J Weiner
Journal:  Neurology       Date:  1973-11       Impact factor: 9.910
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